Habitat: Cultivated worldwide.
Collection: The bulb with its numerous cloves should be unearthed when
the leaves begin to wither in September. They should be stored in a cool dry
Part Used: Bulb.
Actions: Anti-microbial, diaphoretic, cholagogue, hypotensive,
- Volatile oil, consisting of sulphur-containing compounds, including allicin
(=S-allyl-2-propenthiosulphinate), allyl-methyltrisulphide, diallyldisulphide,
diallyltrisulphide, diallyltetrasulphide, allylpropyldisulphide, ajoene,
2-vinyl-4H-l, 3 dithiin, and alliin, which breaks down enzymatically to allicin;
with citral, geraniol linalool and a- and b-phellandrene
- Miscellaneous; enzymes including allinase, B vitamins, minerals flavonoids.
Indications: Garlic is among the few herbs that have a universal usage
and recognition. Its daily usage aids and supports the body in ways that no
other herb does. It is one of the most effective anti-microbial plants
available, acting on bacteria, viruses and alimentary parasites. The volatile
oil is an effective agent and as it is largely excreted via the lungs, it is
used in infections of this system such as chronic bronchitis,
respiratory catarrh, recurrent colds and influenza. It may
be helpful in the treatment of whooping cough and as part of a broader
approach to bronchitic asthma. In general it may be used as a
preventative for most infectious conditions, digestive as well as respiratory.
For the digestive tract it has been found that Garlic will support the
development of the natural bacterial flora whilst killing pathogenic organisms.
In addition to these amazing properties, Garlic have an international
reputation for lowering both blood pressure, blood cholesterol levels and
generally improving the health of the cardio-vascular system. A recent study
was conducted on two groups, one consisting of 20 healthy volunteers who were
fed Garlic for 6 months and the other of 62 patients with coronary heart
disease and raised serum cholesterol. Beneficially changes were found in all
involved and reached a peak at the end of 8 months. The improvement in
cholesterol levels persisted throughout the 2 months of clinical follow-up.
The clinicians concluded that the essential oil of Garlic possessed a distinct
hypolipidemic, or fat reducing, action in both healthy people and patients with
coronary heart disease. Garlic should be thought of as a basic food that
will augment the body's health and pretect it in general. It has been used
externally for the treatment of ringworm and threadworm.
Preparations & Dosage: A clove should be eaten three times a day.
If the smell becomes a problem, use Garlic oil capsules, take three a day as a
prophylactic or three times a day when an infection occurs.
alanine 1, 320-3, 168
allicin 1, 500-27, 800
alliin 5, 000-10, 000
desgalactotigonin 400 rt
3, 5-diethyl-1, 2, 4-trithiolane
glutamic-acid 8, 050-19, 320
2, 3, 4-trithiapentane
Citations from the Medline database for Allium sativum
Aboul-Enein AM: Inhibition of tumor growth with possible immunity
by Egyptian garlic extracts.
NAHRUNG 1986; 30(2):161-9
Garlic bulbs (Allium sativum) were extracted with distilled water or ethanol.
The extracts were then incubated with Ehrlich ascites carcinoma cells at 37
degrees C for 1 h. These pretreated cells were injected into swiss albino mice
which survived over 12 weeks. To the contrary, tumor cells which were
pretreated with garlic extracts, produced ascites tumor in all mice that died 2
or 4 weeks after intraperitoneal injection. When mice were treated twice at
intervals of 7 days with freshly prepared tumor cells exposed to watery or
ethanolic extracts of fresh garlic, they acquired resistance against a
challenge with Ehrlich ascites tumor cells. Administration of garlic extracts
to mice for at least 2 weeks before tumor transplantation, caused a slight
delay of 10-20 days in tumor growth and animal death. Generally, the ethanolic
extract of garlic gave more pronounced effect as tumor inhibitor as well as
immunityinduction than watery extract. No change in serum
electrophoreticpattern was detected in mice, whether the tumor cells injected
wereincubated or not with garlic extract. In animals treated withunincubated
tumor cells, albumin and globulin percentages as well as albumin: globulin
ratios (A/G) were decreased as compared to normalmice. A/G ratio was also
decreased in immunized mice, pretreated with garlic extract, due to the
increase of gamma globulin and unchanging of albumin.
Adoga GI: Effect of garlic oil extract on glutathione reductase levels in
rats fed on high sucrose and alcohol diets: a possible mechanism of the
activity of the oil.
BIOSCI REP 1986 Oct; 6(10):909-12
The effect on glutathione reductase activities of feeding garlic oil to white
albino rats maintained on high sucrose and alcohol diets was studied. Whereas
high sucrose and alcohol diets resulted in significant increases in the
activity of glutathione reductase in liver, kidneys and serum, the presence of
garlic oil restored the levels to near normal. It is proposed that the
mechanism of this action of garlic oil involves the active principle, diallyl
disulphide, which interacts in an exchange reaction with enzymes and substrates
such as glutathione reductase and glutathione which contain thiol groups.
Adoga GI Osuji J: Effect of garlic oil extract on serum, liver and
kidney enzymes of rats fed on high sucrose & alcohol diets.
BIOCHEM INT 1986 Oct; 13(4):615-24
High levels of alkaline phosphatase and alcohol dehydrogenase were observed
in the serum, liver and kidneys of rats fed on high sucrose and high alcohol
diets over a period of 75 days. Garlic oil extract fed with any of the diets,
significantly lowered the high levels of the two enzymes in the serum, liver
and kidneys. This effect may be due to reduced biosynthesis of fatty acids as
NADPH, required for the process, is utilised for the metabolism of the oil.
Ahn-B-W; Lee-D-H; Yeo-S-G; Kang-J-H; Do-J-R; Kim-Y-H; Park-Y-H