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N-Acetylcysteine (NAC): An Old Nutrient Attracts New Research


(2 of 6)  


1. Slowing AIDS: The roles of NAC and vitamin C.Passwater, Richard A.Whole Foods (Jan. 1992)

2. Human Aging Research: Part TwoPasswater, Richard A. and Welker, Paul A.Amer. Lab. 3(5):21-6 (May 1971)

3. Enhancement of ischaemic rabbit skin flap survival with theantioxidant and free-radical scavenger N-acetylcysteine.Knight, K., et al,Clin. Sci. 81:31-6 (1991)

4. Antioxidant activity and other mechanisms of thiols involvedin chemoprevention of mutation and cancer.De Flora, Silvio, et al,Amer. J. Med. 91(Suppl 3C):122S-130S (Sep. 30, 1991)

5. Bioavailability of dietary glutathione: Effect on plasmaconcentration.Hagen, Torie M., et al,Amer. J. Physiol. Gastrointest. Liver Physiol. 259(4):22-4(1990) and Amer. J. Physiol. 259:G524-G529 (1990)

6. Glutathione-mediated transport across intestinal brush-bordermembranes.Vincenzini, M. T., Favilli, F. and Iantomasi, T.Biochim. Biophys. Acta, Ser. Biomembr. 942(1):107-14 (1988)

7. Glutathione and Aflatoxin B-1 induced liver tumors: Evidencethat the intact glutathione molecule is required by theneoplastic tissue to undergo regression of malignancy.Novi, A. M., Florke, R. and Stukenkemper, M.Science 212:541-2 (1981)

8. Exogenous glutathione protects intestinal epithelial cellsfrom oxidative injury.Lash, Lawrence H., et al,Proceed. Natl. Acad. Sci. 83:4641-5 (1986)

9. AcetylcysteineEditorialThe Lancet 337(8749):1069-70 (May 4, 1991)

10. Systemic glutathione deficiency in symptom-free HIV-seropositive individuals. Buhl, Roland, et al.,The Lancet 2(8675):1294-8 (Dec. 2, 1989)

11. Glutathione concentrations in plasma and blood are markedlydecreased in HIV-infected children.Smith, C. V., et al.,Int. Conf. AIDS 6(2):368 (abst. # 2058) (June 20-3, 1990)

12. Metabolic disorder as early consequence of SimianImmunodeficiency Virus infection in Rhesus macaques.Eck, Hans-Peter, et al,Lancet 338:346-7 (Aug. 10, 1991)

13. Blood antioxidant status and erythrocyte lipid peroxidationfollowing distance running.Duthie, G., et al.Arch. Bioch. 282:78-83 (1990)

14. Protective Effect of Vitamin E On Exercise-induced OxidativeDamage in Young and ELderly Subjects.Meydani, M., et al.International Society for Free Radical Research, 5th BiennialMtg. Pasadena, CA (Nov. 14-20, 1990)

15. Spintrappers and Vitamin E prolong endurance to musclefatigue in mice.Novelli, G., et al.Free Rad. Bio. Med. 8:9-13 (1990)

16. Lp(a) lipoprotein as a risk factor for myocardialinfarction.Rhoads, G. G., et al,JAMA 256:2540-4 (1986)

17. Apolipoprotein(a), A1 and B and parental history in men withearly onset ischaemic heart disease.Durrington, P. N., et al,Lancet I 1070-3 (1988)

18. Lipoprotein(a) modulation of endothelial cell surfacefibrinolysis and its potential role in atherosclerosis.Hajjar, K. A., et al,Nature 339:303-5 (1989)

19. Lipoprotein(a)EditorialLancet 337:397-8 (Feb. 16, 1991)20. Lipoprotein(a): A possible link between lipoproteinmetabolism and thrombosis.Rees, AlanBrit, Heart J. 65:2-3 (1991)

21. Inverse correlation between plasma vitamin E and mortalityfrom ischemic heart disease in cross-cultural epidemiology.Gey,, K. Fred, et al,Amer. J. Clin. Nutr. 53:326S-34S (1991)



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     by Richard Passwater

Richard A. Passwater, Ph.D. has been a research biochemist since 1959. His first areas of research was in the development of pharmaceuticals and analytical chemistry. His laboratory research led to his discovery of ...more

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