An enlightening article entitled The Tomato Effect-Rejection
of Highly Efficacious Therapies was published by the American
Medical Association in JAMA, 1984; 251:2387-2390. In this article,
Drs. James S. Goodwin and Jean M. Goodwin describe the tomato
effect in medicine:
The tomato effect in medicine occurs when an efficacious treatment
for a certain disease is ignored or rejected because it does not "make sense"
in the light of accepted theories of disease mechanism and drug action. The tomato was largely
ignored because it was clearly poisonous; it would have been foolish to eat one. In
analogous fashion, there have been many therapies in the history of medicine that, while later
proved highly efficacious, were at one time rejected because they did not make sense. ...We
contend that the tomato effect is in its own way every bit as influential in shaping
modern therapeutics as the placebo effect... Recognition of the reality of the tomato effect,
while not preventing future errors, may at least help us better understand our mistakes.
***
It would seem, ...that modern medicine is particularly vulnerable
to the tomato effect. Pharmaceutical companies have increasingly turned to theoretical
over practical arguments for using their drugs... What is lost in such discussions
are the only three issues that matter in picking a therapy: Does it help? How
toxic is it? How much does it cost? In this atmosphere we are at risk for rejecting
a safe, inexpensive, effective therapy in favor of an alternative treatment perhaps less
efficacious and more toxic, which is more interesting in terms of our latest views of disease
pathogenesis. (Emphasis added)
In an age when nearly half of the coronary artery bypass surgeries
conducted in the United States are recognized as being conducted
for inappropriate reasons and the efficacy of such surgery has
been frequently called into question, in contrast to the successful
experience physicians have had with chelation, it appears that the "tomato effect" has indeed taken place with chelation therapy. The efficacious use of this therapy in
treating arteriosclerosis has been demonstrated in patients world-wide.
It is only in recent years that the scientific rationale to explain
the benefits of chelation therapy has been elucidated in published
research on free radical pathology.
In Rogers v. State Board of Medical Examiners, 371 So.
2d 1037 (Fla. App. 1979) aff'd, 387 So. 2d 937 (Fla. 1980),
the court discussed the right of the State Board of Medical Examiners
to prohibit a physician from administering chelation therapy.
Acting Chief Judge Boyer noted that provisions of the Constitution
grant a person certain inalienable rights, from which derive the
right of a patient to receive, pursuant to a voluntary election,
chelation therapy, and in the absence of unlawfulness, harm, fraud,
coercion of misrepresentation, the Board was without authority
to prohibit the physician from administering such therapy. Id,
at 1041.
Utilization of a therapy which is different is not unprofessional
or unethical conduct. The converse would also hold true. General
acceptance of a therapy does not mean that utilization of that
therapy is necessarily professional or competent. Many therapies
and treatments thought to be "proper" have now been
abandoned as barbaric. The use of alternative means of treatment
should not arbitrarily be deemed incompetent care.
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