Both extracted and synthesized caffeine may be added to other products. Many common pharmaceutical preparations contain caffeine for its stimulating effects to counteract sedating antihistamines or for its cerebral vasodilating effects to relieve vascular headaches. Cafergot is a prescription drug containing caffeine and is used for migraines; thus, caffeine can help reduce headaches or cause them, which is more common.

Some people run their bodies on caffeine and not on their basic life force and the natural energy of their hormones, such as adrenal and thyroid. Caffeine, although it is not seriously addicting, is very habit forming. It is not particularly good for athletes or anyone seriously interested in their health. Although it may improve muscular work and short-term performance in both physical and mental athletes, it creates depletion by its diuretic nutrients, and foods can help balance this.