Sundaram SG Milner JA

Antitumor effects of organosulfur compounds present in garlic against canine mammary tumor cells (Meeting abstract).

In: FASEB J (1992) 6(4):A1391

Sutabhaha S Suttajit M Niyomca P

Studies of aflatoxins in Chiang Mai, Thailand.

In: Kitasato Arch Exp Med (1992 Apr) 65(1):45-52

Tadi PP

ANTICARCINOGENIC, ANTITUMOR, AND ANTIFUNGAL PROPERTIES OF ALLIUM SATIVUM

In: Diss Abstr Int [B] (1992) 52(8):4144

Takada N Matsuda T Otoshi T Yano Y Otani S Hasegawa T Nakae D Konishi Y Fukushima S

Enhancement by organosulfur compounds from garlic and onions of diethylnitrosamine-induced glutathione S-transferase positive foci in the rat liver.

In: Cancer Res (1994 Jun 1) 54(11):2895-9

Tatarintsev A Makarova T Karamov E Kornilayeva G Vrzheshch P Schegolev A Yershov D Turgiev A

Ajoene blocks HIV-mediated syncytia formation: possible approach to 'anti-adhesion' therapy of AIDS.

In: Int Conf AIDS (1992 Jul 19-24) 8(3):39 (abstract no. PuA 6173)

OBJECTIVES: Ajoene, (E, Z)-4, 5, 9-trithiadodeca-1, 6, 11-triene-9-oxide, isolated from extracts of garlic (Allium sativum) has previously beenshown to inhibit platelet aggregation by inactivating allostericallythe platelet integrin, GP IIb/IIIa (Apitz-Castro R et al: BBRC 1986141:145). Structural and functional similarity of integrins led us topropose that ajoene may also inhibit adhesive interactions ofleukocytes. Since integrin-mediated formation of cell-to-cellcontacts has been shown to be an essential prerequisite for membranefusion (Hildreth JEK, Orentas RJ: Science 1989 244:1075) we alsoattempted to evaluate