Dosage and preparations
As one of the more aesthetic herbal remedies, a very pleasant tea can be made from 1-2 teaspoonfuls of the dried berries infused in hot water and drunk regularly. 1ml of the tincture are taken 3 times daily, then morning & evening as a maintenance dose. This may be taken over long periods of time as their is no fear of toxicity problems. Up to 5ml three times daily can taken quite safely.

Citations from the Medline database for the genus Crataegus: Hawthorn

Ammon HP Handel M

[Crataegus, toxicology and pharmacology. Part III: Pharmacodynamics and pharmacokinetics]

Planta Med (1981 Dec) 43(4):313-22 Published in German

Ammon HP Handel M

[Crataegus, toxicology and pharmacology. Part II: Pharmacodynamics (author's transl)]

Planta Med (1981 Nov) 43(3):209-39 Published in German

Ammon HP Handel M

[Crataegus, toxicology and pharmacology, Part I: Toxicity (author's transl)]

Planta Med (1981 Oct) 43(2):105-20 Published in German

Beier A Konigstein RP Samec V

[Clinical experiences with a crataegus pentaerythrityl-tetranitrate combination drug in heart diseases due to coronary sclerosis in old age]

Wien Med Wochenschr (1974 Jun 15) 124(24):378-81 Published in German

Blesken R

[Crataegus in cardiology]

Fortschr Med (1992 May 30) 110(15):290-2 Published in German

The fact that the effectiveness of numerous phyto-preparations, so- called, has been demonstrated to the satisfaction of traditional medicine has led to increasing interest in phytotherapy. This also applies to Crataegus (whitethorn), the effects of which have been demonstrated in numerous pharmacological studies. These effects, produced mainly by the flavonoids, indicate a simultaneous cardiotropic and vasodilatory action, as confirmed clinically in controlled double-blind studies. This means that Crataegus can be employed for cardiological indications for which digitalis is not (yet) indicated. Prior to use, however, a Crataegus preparation must meet certain preconditions with respect to dosage, pharmaceutical quality of the preparation, and an accurate definition of the later.

Ciplea AG Richter KD

The protective effect of Allium sativum and crataegus on isoprenaline- induced tissue necroses in rats.

Arzneimittelforschung (1988 Nov) 38(11):1583-92

Di Renzi L Cassone R Lucisano V Leggio F Gambelli G

[On the use of injectable crataegus extracts in therapy of disorders of peripheral arterial circulation in subjects with obliterating arteriopathy of the lower extremities]

Boll Soc Ital Cardiol (1969) 14(4):577-85 Published in Italian

Fehri B Aiache JM Boukef K Memmi A Hizaoui B

Valeriana officinalis & C. oxyacantha: toxicity from repeated administration

J Pharm Belg (1991 May-Jun) 46(3):165-76 Published in French

Hammerl H Kranzl C Pichler O Studlar M

[Clinico-experimental metabolic studies using a Crataegus extract]

Arztl Forsch (1967 Jul 10) 21(7):261-4 Published in German

Kharchenko NS

[Medicinal value of Crataegus ucrainica]