"The
mind steadfastly refuses to behave locally, as contemporary scientific
evidence is beginning to show. We now know, for example, that brainlike
tissue is found throughout the body... So, even from the conservative perspective
of modern neurochemistry, it is difficult if not impossible to follow a
strictly local view of the brain." C
Larry Dossey, M.D.[1]
In
the conduct of medical research, the existence of mind/body interactions
has, over the years, been treated as a sort of hindrance. Such interactions
are often lumped under the somewhat disparaging name of the "placebo response."
"Placebo" is a Latin term whose original meaning is "I shall please," and
it refers to the mysterious and uncharted mechanisms by which the power
of suggestion can result in a physiological change.
Ironically,
the very scientific methods championed by mainstream medicine in the testing
of drugs have provided the greatest scientific support for the existence
and power of the mind/body connection. In fact, the mechanisms involved
are so formidable that the standard research procedure requires separating
out their effects from those of the drug.
Hence,
the power of mind/body mechanisms has been examined and measured in virtually
thousands of drug studies. It is in this sense that they have been verified
and acknowledged by medical research to be a real and powerful phenomenon.
In
the decades of the seventies and eighties, researchers trained their sites
more directly onto these mechanisms. Herbert Benson, M.D. and his colleagues
at Harvard Medical School led the way with the discovery of "the relaxation
response." This work has led to a cascade of findings about how mind/body
mechanisms can be used for medically significant impact on hypertension,
heart disease, cancer and other conditions.
Today,
leading edge programs for both patients and professionals are now conducted
at Harvard's Mind/Body Medical Institute, New England Deaconess Hospital,
Boston. And, under Benson's direction, the Institute is collaborating in
the creation of other such programs at major medical centers around the
nation.
In
Benson's perspective, "We are part of mainstream medicine, we are not alternative.
You might say that this was considered alternative years ago, but it is
now mainstream."[2]
Taking
Center Stage
Indeed
he may be right. In early 1993, a widely reported study documented the
surprising popularity of alternative medicine in this country. Published
in the New England Journal of Medicine and led by Harvard researcher
David Eisenberg, M.D., the study found that one in three adults had used
some form of unconventional medicine. Of the varieties reported, mind/body
techniques were the most frequently used.[3]
This followed by just a few months the creation of the Office of Alternative
Medicine in the National Institutes of Health. And shortly thereafter,
mind/body medicine was brought into the living rooms of millions of Americans
by a television series called "Healing and the Mind," hosted by the popular
journalist Bill Moyers on PBS.
What
is the emerging role of this work? Benson regards it as an integral part
of comprehensive health care. He offers the metaphor of a three legged
stool: "One leg is pharmaceuticals, another is surgery, and the third is
what you can do for yourself. Mind/body medicine is strengthening the third
leg, integrated with the other two legs."[4]
KEY
PRINCIPLES
The Biopsychosocial
Perspective
In
the late 1970's the eminent medical researcher George Engel of the University
of Rochester made the bold statement that modern medicine needed a new
way of thinking about health and illness.[5]
He proposed what he called the "bio-psycho-social" model, in which health
is the outcome of many factors interacting together. This provides the
theoretical framework underpinning mind/body medicine.
In
this view, health is not just a matter of "the drugs keeping up with the
bugs." Rather, health is determined by an interaction among our genetic
vulnerabilities; environmental inputs such as germs, viruses, or pollutants;
psychological factors such as stress, lifestyle, attitudes, and behavior;
and social factors such as supportive relationships, economic well being,
access to health care, and family and community patterns of behavior.
Engel's
perspective is gradually penetrating the thinking of mainstream medicine.
When we look at the big picture of all the factors that influence health,
we can see that many are within our direct control. Along with this new
way of thinking has come a growing openness and receptivity to the contributions
of mind/body approaches.
Mind/Body
Communication
Our
thoughts and feelings influence the body via two kinds of mechanisms: the
nervous system and the circulatory system. These are the pathways of communication
between the brain and the rest of the body.
The
brain reaches into the body via the nervous system. This allows it to send
nerve impulses into all the body's tissues and influence their behavior.
The brain can thus affect the behavior of the immune system with its nerve
endings extending into the bone marrow (the birthplace of all white cells),
the thymus, the spleen, and the lymph nodes.
It
also reaches into all the glands of the endocrine system, all the bones,
muscles, all the internal organs, and even the walls of veins and arteries.
It can influence the behavior of the heart with its nerves penetrating
the heart tissue, affecting heart rate and other aspects of the heart's
functioning. The entire body is literally "wired" by the brain.
The
brain is also a gland. It manufactures thousands of different kinds of
chemicals and releases them into the bloodstream. These chemicals circulate
throughout the body and influence the activity and behavior of all the
body's tissues. The brain could be described as the ultimate apothecary,
producing many more drugs than science has ever invented.
Finally,
the mind/body connection is a two-way street. In addition to sending messages
into the body's tissues, it also receives feedback, both in the form of
nerve impulses and its own receptors that sense what chemicals are being
released by other tissues in the body.
Research
into how the brain can influence immune responses has given rise to the
new field called "psycho-neuro-immunology" (PNI).
Findings in this field have brought great hope to people dealing with such
difficult illnesses as cancer, AIDS, CFIDS (chronic fatigue immune dysfunction
syndrome), and other immune-related diseases.
It
is only a matter of time before similar acronyms are defined for other
fields such as "psycho-neuro-cardiology" (PNC),
the study of the mind-heart connection; or "psycho-neuro-hematology"
(PNH), the study of how the mind can influence blood-related disorders,
such as clotting problems in hemophilia.
The
Power of the Mind/Body Connection.
One of the most stirring stories about the power of the mind/body connection
concerns a man who was diagnosed with terminal cancer. It was reported
by Dr. Bruno Klopfer in a medical journal
in the late 1950's. It involves a man with metastatic
cancer and tumors which had spread throughout his body. The patient had
tried every available form of medicine, and his condition had hopelessly
deteriorated to the point where he was bedridden and gasping for air.
His
doctors agreed that he had only a few days to live. Then the man heard
about an experimental drug called Krebiozen
which was in the process of being tested. He insisted on being included
in the experimental trials. His doctors, feeling he had nothing to lose
and would soon be dead anyway, agreed out of compassion to give him the
experimental drug. To their amazement, the man's tumors soon began to shrink
dramatically, and he was discharged from the hospital.
Two
months later, the man read news accounts of the research on Krebiozen
which reported serious doubts with the drug. Within a matter of days, the
man's tumors had returned and were again threatening his life. His doctor
cleverly convinced him that a new and more potent shipment had been received,
and proceeded to give him injections of plain water. His tumors once again
began to shrink dramatically. He remained healthy for several more months,
until another news report declaring "Nationwide AMA Tests Show Krebiozen
to be Worthless as a Cancer Treatment." The man died within two days.[6]
The Stress
Response
The
stress response is a set of changes in the body that result when the person
experiences what they perceive to be a challenging or threatening situation.
This matter of "perceived threat" is important because the effects of the
stress response on the body are the same, whether the threat is real
or just imagined in the mind.
Commonly
called the "fight or flight" reaction, the stress response has the beneficial
effect of preparing the body to function at a higher level of efficiency
which, of course, enhances the likelihood of survival. The physiological
changes include:
!
Increased blood pressure
!
Increased respiratory rate
!
Increased heart rate
!
Increased oxygen consumption (burning of fuel)
!
Increased blood flow to skeletal muscles
!
Increased perspiration
!
Increased muscle tone
While
all these changes clearly contribute to one's ability to fight or flee
in an emergency, they also have a downside. If the person is experiencing
the stress response regularly and for extended periods of time, these physiological
changes have the effect of weakening the body's resistance to illness and
lowering the effectiveness of its mechanisms of self-repair.
The Relaxation
Response
Another
key principle is the relaxation response which was discovered and named
by Herbert Benson, M.D. and his colleagues in 1974.[7],[8]
They were studying a pattern of physiological changes that occurs in people
practicing Transcendental Meditation (TM).
This
pattern of changes has been found to represent a very beneficial state,
one that is virtually a mirror image of the stress response. The relaxation
response includes the following changes:
!
Reduced blood pressure
!
Reduced respiratory rate
!
Reduced heart rate
!
Reduced oxygen consumption (burning of fuel)
!
Reduced blood flow to skeletal muscles
!
Reduced perspiration
!
Reduced muscle tension
The
relaxation response is an antidote to the effects of the stress response,
and it has also been found to enhance the effectiveness of the body's defenses
and self-repair mechanisms. Regular practice of techniques that elicit
this response also brings improved emotional well-being, and better handling
of stressful life events.
The
relaxation response is a physiological state, not a technique as such.
As we shall see later, there are many techniques that can be used to produce
it and, indeed, learning to do this is at the heart of mind/body medicine.
Coping,
Emotions, and Health
Researchers
have identified how the ways we cope with emotions and stressful situations C
our "coping styles" C
can influence our physical health. Most firmly established are the links
between coronary heart disease and the Type A behavior pattern. Type A
is a way of coping characterized by constant hurriedness, intense competitiveness,
and free-floating hostility.
The
middle ground, or Type B, is considered a more balanced way of coping that
involves appropriate expression of all emotions, and the ability to meet
one's own needs while responding to those of others. People who cope in
this more balanced way tend to be less at risk for serious illness. The
cultivation of these behaviors is often a goal in mind/body medicine programs,
especially for heart disease and cancer.
Lifestyle
Change
The
use of mind/body medicine takes place within a broader context of changing
one's lifestyle to promote health. Making a daily practice of mind/body
techniques is but one of several areas of lifestyle change that work together
in a synergistic way. Other areas include proper diet, exercise, and social
support.
While
the health benefits of diet and exercise are obvious, there is a growing
body of research now indicating that supportive interpersonal relationships
are strongly associated with better health. They seem to ameliorate or
"buffer" the harmful effects of stress on the body.
VARIATIONS:
THE MANY CONTEXTS OF MIND/BODY MEDICINE
Its
variety of techniques may be used by medical doctors, nurses, physician's
assistants, naturopaths, osteopaths, practitioners of Chinese medicine
and ayurveda, bodyworkers,
homeopaths, and chiropractors. Other human service providers such as psychologists,
clinical social workers, marriage and family counselors, ministers, and hypnotherapists
also use these tools. And of course there are very specialized applications
for midwives, physical therapists, exercise physiologists, respiratory
therapists and others.
Mind/body
approaches are generally taught either in office practice via private consultation
with a health care provider, or in group programs. Hospitals and other
institutions offer various kinds of support groups or group therapy programs
for people with cancer, heart disease, organ transplantation and other
conditions. Almost all such programs incorporate some use of mind/body
techniques such as relaxation exercises or imagery.
These
methods are often taught to patients who are preparing to undergo surgery
or other difficult treatments. Such preparation has been found in research
to speed healing, reduce bleeding and complications, and result in earlier
discharge from the hospital.
PROCEDURES
AND TECHNIQUES
The
repertoire of mind/body medicine includes all psychological strategies
which directly influence physiological states. Following are the most commonly
used methods.
There
are hundreds of varieties of meditation. The most basic approach for facilitating
the relaxation response is that described by Herbert Benson. The process
should take place in a quiet environment, a setting where one can be quiet,
undisturbed, and in a comfortable position for at least fifteen to twenty
minutes. Given this setting, there are only two essential steps: the silent
repetition of a word, sound, phrase, or prayer; and the passive return
back to the repetition whenever other thoughts intrude.
Variations
on these instructions are at the core of many forms of meditation from
diverse spiritual traditions. The simplicity of these instructions, however,
makes the approach available to virtually anyone, regardless of their spiritual
or religious beliefs. This is because the person can use as their repetitive
focus a prayer or any other words that reinforce their beliefs (e.g., "God
is love"), thereby adding a further dimension of comfort to the experience.
Mindfulness
This
is actually another approach to meditation, which involves the ability
to focus completely on only one thing at a time. In other words, in mindfulness
the mind is full of whatever is happening right now. This can include walking,
cooking, sweeping the floor, dancing, watching a bird, hearing the sound
of a river, or any other focus you may choose. Whenever thoughts intrude,
you simply return your attention back to the focus. This is a traditional
Buddhist approach, and has been widely popularized by Jon Kabat-Zinn,
Ph.D. in the Stress Reduction Clinic at the University of Massachusetts
Medical Center in Worcester.
This
is another common approach to eliciting the relaxation response. In this
technique the body itself is used as the focus of attention. It may be
done either lying down or sitting. The technique involves progressing through
the body one muscle group at a time, beginning with the feet, moving up
the legs, and so on, spending approximately a minute in each area. For
each muscle group, you hold or clench the muscles in the area for a count
of ten, and then release for a count of ten, before moving on to the adjacent
area.
The
remaining techniques described below, while they also can lead to induction
of the relaxation response, are also used for other purposes.
Mental
Imagery
This
involves using symbols to imagine that the changes you desire in your body
are actually happening. For example, you might imagine that pain is melting
away and dripping like a warm liquid out of your finger tips. Or you might
develop an image of your immune cells actively subduing and preying on
cancer cells or viruses, like birds of prey swooping down to engulf field
mice in a meadow. This is a highly personalized technique, and you would
use images that are uniquely exciting and meaningful to you.
Autogenic
Training
This
approach involves using a combination of autosuggestion and imagery. Phrases
are used to describe to oneself what changes in the body are desired, as
if they are happening now. For example, "My legs are warm and heavy," "All
the muscles of my back are softening and melting," "I am calm," and "Warm,
peaceful relaxation is flowing throughout my body." These phrases are repeated
while maintaining one's focus on those parts of the body being addressed.
Whenever the mind wanders, the attention is gently and passively returned
to the focus.
Breath
Therapy
A
variety of breathing exercises can help one to release tension, anxiety
and pain. They can be used in conjunction with imagery or autosuggestion.
They can also be used to encourage fuller breathing n general and give
the body a greater supply of energy, which it can use for healing. It takes
energy to fuel the body's self-rep[air mechanisms including the immune
system. Since we take a thousand breaths every hour, each breath is an
opportunity to contribute to a healing process.
Some
breath therapy techniques use the breath in a calm, peaceful way to induce
relaxation, to release pain, or to prepare for imagery. Another variety
is Evocative Breath Therapy (EBT) which uses stronger breathing, sometimes
accompanied by music, to stimulate emotions and emotional release.
A
simple description of hypnosis is offered by Karen Olness,
M.D., of Case Western Reserve University who calls it "a form of self-induced,
focused attention that can make it easier for you to relax or learn to
control your body's functions."[10]
It is this experience of extraordinary focus of attention that makes it
possible to influence bodily states.
When
in a hypnotic state, the mind is perfectly aware of the surroundings and
the situation, but because it is so highly focused, it is able to concentrate
on a task without being easily distracted. This enables the person to use
imagery, relaxation, or autogenic suggestions
in a richer, more powerful way.
Hypnosis
is especially useful for relief from pain, reducing the distress from other
symptoms or the side effects of treatment, and establishing a greater sense
of control. Hypnotic states can be self-induced or can be facilitated by
a hypnotist or hypnotherapist. Finally,
it can help in overcoming one's resistance to healthful behavior change,
such as reducing smoking or changing one's eating habits.
Biofeedback
Biofeedback
uses special instruments attached to the body to give the person information
about what is happening in the body. The instruments serve to amplify the
signals that the person may not otherwise be able to detect, so they can
then use this visual or auditory "feedback"
to learn to regulate certain bodily functions. Many people find this form
of assistance very helpful for learning to relax.
Other
kinds of biofeedback include thermal, sensing the temperature of
the skin as an indication of blood flow and relaxation; electrodermal
(EDR), measuring subtle changes in amounts of perspiration; finger pulse
for measuring heart rate and force, useful for anxiety or cardiovascular
symptoms; and monitoring breathing patterns C
rate, volume, rhythm, and location (belly or chest) of each breath.
Biofeedback
has many applications, including headache and migraines, anxiety, chronic
pain, teeth grinding and clenching, Raynaud's
disease (cold hands), incontinence, asthma, and muscle disorders including
helping people learn to re-use arms or legs that have been traumatized.
Essentially any bodily process that can be measured can potentially be
controlled or influenced through the help of these techniques.
SCIENTIFIC
SUPPORT
There
are four areas of research that support mind/body medicine: studies describing
the physiology of mind/body interactions, those measuring the effects of
mind/body therapy techniques, research on the health outcomes of structured
mind/body programs employing a variety of techniques, and studies of cost
effectiveness.
The
Mind/Heart Connection.
Scientists have pieced together how stress affects the heart. This work
is well-summarized by Cynthia Medich, Ph.D.,
R.N., a cardiovascular specialist and researcher at the Mind/Body Medical
Institute, Harvard Medical School and New England Deaconess Hospital, Boston.
What Medich describes as "the mind-heart
connection" involves the release of two kinds of stress hormones into the
bloodstream: corticosteroids and catecholamines.
These
hormones set off a cascade of changes in the body including increased platelet
aggregation (tendency for blood cause clotting); increased coronary artery
tone; a surge in coronary artery pressure; increased blood pressure, glucose
levels, and lipid levels; a more rapid and powerful heart beat; and, paradoxically,
a constriction in the coronary arteries. In short, the demands on the heart
all increase.[11]
With
this understanding it is easy to see how individuals who experience stress
on a chronic basis are at greater risk for heart diseases. This connection
was dramatically illustrated in a study of air traffic controllers, considered
to be in a very stressful occupation, who were found to have five times
the incidence of hypertension as a comparison group of second class airmen.[12]
Other
research has been able to anticipate who will develop hypertension and
heart disease. One study followed 1100 adults for 20 years. Those who had
the highest levels of anxiety at the beginning of the study turned out
to have the highest rates of hypertension two decades later.[13]
An
eight year study of over three thousand people found that those with the
Type A behavior pattern were twice as likely as Type B's to develop coronary
heart disease.[14]
A
ten-year study was conducted to follow the mortality rates of people who
had experienced stroke. Those who had been diagnosed with either major
or minor depression were 3.4 times as likely to have died within the follow-up
period. The death rate among depressed patients with few social contacts
was especially high: over 90% had died.[16]
In
a study of 194 heart attack patients, those who reported lower amounts
of emotional support in their lives were nearly three times as likely
to die within six months as those with higher levels of emotional support.[17]
The
Mind and Immunity.
In addition to affecting the heart, the chemistry of the stress response
has been found to lower immune functioning. This is illustrated by studies
of the effects of exam stress on medical students which have found: significant
drops in the activity natural killer (NK) cells[18]
as well as in the numbers[19],[20]
of NK cells (NK cells are a key in fighting cancer cells and viruses);
and significantly lower percentage of T-helper cells in the blood[21],[22]
(the cells that arouse the immune response to fight off an infection).
In
a study of recently divorced people, those who wanted the divorce, for
whom it brought relief, were found to have better immunity than those who
did not want the divorce.[23]
Research
has shown that depression can have an adverse effect on immunity.
A study that took place in a mental hospital compared natural killer (NK)
cell activity in depressed patients, schizophrenic patients, and staff
members. The patients with major depressive disorder had significantly
lower NK functioning than schizophrenic patients and staff members.[25]
A
study involved 132 college students to determine the effects of positive
emotions on S-IgA levels. Half watched a morbid
documentary about power struggles in World War II, while the other half
watched an inspiring film about Mother Theresa, a Roman Catholic nun selflessly
serving the poor and sick in Calcutta. The latter group had significantly
increased S-IgA concentrations, indicating heightened
immune responsiveness.[26]
Mind/body
researcher Lydia Temoshok, Ph.D. studied
the psychological factors associated with malignant melanoma. Among her
findings was the discovery that emotional expressiveness was directly
related to the thickness of the patients' tumors, as well as the course
of their disease.[27],[28]
Major
findings of Temoshok's research include
the following:
!
Patients who were more emotionally expressive had thinner tumors and more
slowly dividing cancer cells.
!
The more emotionally expressive patients had a much higher number of lymphocytes
(immune cells) invading the base of the tumor.
!
Patients who were less emotionally expressive had thicker tumors and more
rapidly dividing cancer cells.
These
findings helped contribute to the formation of the concept of "type C"
coping .
Can
the immune system be trained to respond, like Pavlov's dog was trained
to salivate at the sound of a bell? In a well-designed, controlled study,
participants were given a sherbet sweet along with a subcutaneous injection
of a chemical known to increase NK cell activity (epinephrine). After several
administrations of this regime, the epinephrine was replaced by a useless
saline injection. Remarkably, the participants still increased their NK
cell activity in response to eating the sherbet accompanied only by
the saline injection.[29]
Techniques
of Mind/Body Medicine
Some
research on techniques has examined their effects on specific bodily functions
such as immune responses, blood pressure, and heart rate. Other studies
have looked at recovery from surgery, and still others have focused on
psychological well-being and the quality of life.
Relaxation
Training. This is
by far the most widely studied subject in this tradition with hundreds
of studies documenting its benefits. A few examples:
Patients
with ischemic heart disease who practiced
the relaxation response daily for four weeks achieved significant reduction
in the frequency of pre-ventricular contractions.[30]
Patients
with hypertension who took an 8 week (once a week) training program achieved
significantly lower blood pressure, and the benefits were maintained three
years later.[31]
Patients
receiving several kinds of elective surgery and who were trained in relaxation
had less surgical anxiety both before and after surgery. The intensity
of their pain and their use of pain medication were both reduced.[32]
A
controlled study of women with premenstrual syndrome (PMS) using the relaxation
response twice daily for three months found a 58% reduction in the severity
of their symptoms.[35]
Two
studies found increased NK cell activity as a result of practicing the
relaxation response. One involved geriatric residents in nursing homes,
and also found indications of lower activity of herpes viruses. In addition,
there were significant reductions in symptoms of emotional distress.[36]
Finally,
in a study of exam stress in medical students, the more they practiced
the relaxation response, the higher was the percentage of T-helper cells
circulating in their blood.[37]
Meditation.
Of many various forms of meditation, TM has led the way in mind/body research.
Over 500 papers have been published in 108 scientific journals, authored
by scientists at 211 research institutions and universities, in 23 countries
worldwide. Studies of TM were instrumental in discovering the relaxation
response and its benefits for hypertension. Other studies have found important
benefits for such diverse populations as prison inmates, drug addicts,
and Vietnam veterans suffering from post-traumatic stress disorders.
Imagery.
Imagery is often used in combination with relaxation and meditation. A
controlled study of 55 women examined the effects of imagery and relaxation
on breast milk production in mothers of infants in a neonatal intensive
care unit. They received a 20 minute audio tape of progressive relaxation
followed by guided imagery of pleasant surroundings, milk flowing in the
breasts, and the baby's warm skin against theirs. They produced more than
twice as much milk as those receiving only routine care.[40]
In
another study, a group of metastatic cancer
patients using daily imagery for a year achieved significant improvements
in NK cell activity and several other measures of immune functioning.[41]
At
Michigan State University, researchers found that students could use guided
imagery to improve the functioning of certain white cells called neutrophils.
(Neutrophils are important immune cells in defense
against bacterial and fungal infection.) They could also decrease, but
not increase, white cell counts. At one point in the study, a form of imagery
intended to increase neutrophil count unexpectedly
caused a drop instead. Subsequently, students were taught imagery explicitly
intended to keep the neutrophil count steady,
while increasing their effectiveness. Both of these goals were achieved.[42]
Breath
Therapy. A study
examined the effect of Evocative Breath Therapy (EBT) on salivary immunoglobulin
A (S-Iga). EBT involves abdominal breathing accompanied
by music and post?hypnotic suggestion to promote emotional arousal and
release. Forty?five adults in a group therapy program for cancer showed
an average 46% increase in S-IgA levels, after
an hour-long EBT experience.[43]
Multi-Strategy
Group Programs
Most
organized mind/body therapy programs use a regimen of several techniques.
Below are described some findings of such "multi-strategy" programs for
specific illnesses.
Hypertension.
A group program for patients with hypertension included training in the
relaxation response, nutrition, exercise, and stress management.[46]
Findings included significant reductions in blood pressure, cholesterol, triglycerides,
weight, percent body fat, and psychological symptoms. Importantly, most
of the benefits were intact when the patients were checked three- to five-years
later.[47]
Surviving
Heart Attacks. Patients
recovering from myocardial infarction took a six-hour program of stress
management training with mind/body techniques and emotional support.
The result was a 50% reduction in subsequent rate of cardiac deaths.[48]
Benefits
for Infertility.
A ten-week group program for infertile women included training in the relaxation
response with instructions for daily practice, and training in stress management,
exercise, nutrition, and group support. Results included decreases in anxiety,
depression and fatigue, and increased vigor. Also, 34% of the women became
pregnant within six months of the program.[50]
Reducing
Symptoms of AIDS.
In a controlled study, patients received group training in biofeedback,
guided imagery, and hypnosis. Results included significant decreases in
fever, fatigue, pain, headache, nausea, and insomnia. There also were significantly
increased vigor and hardiness.[51]
Another
group program for HIV found significant improvement in emotional expression,
sense of control over health, tension, anxiety, fatigue, depression, and
total mood disturbance.[52]
Psychological
Well-Being in Cancer.
Fifty-nine patients took a ten-day, 60-hour group program that includes
imagery, relaxation training, lifestyle evaluation, emotional release therapies,
group support, breath therapy, and learning from the illness experience.
Results included significant improvements in emotional expressiveness,
fighting spirit, quality of life, sense of control over health, and optimism C
including for patients with metastatic
disease. These improvements were still present three months after completing
the program.[53]
Increasing
Survival Time in Malignant Melanoma.
The patients who participated in the above study were followed for six
years. A startling difference in death rates between the two groups was
found. Of those who were in the control group (no group therapy), 13 of
34 had a recurrence of cancer during the six years and 10 died. For those
who had the group program, only 7 of 34 had recurrences and only 3 died.[55]
Increasing
Survival Time in Breast Cancer.
A ten-year controlled study was conducted with 86 women with metastatic
breast cancer. Those who had a year of weekly group sessions had nearly
double the survival time of those who did not have the group (averaging
36 months versus 18 months). The group provided self-hypnosis and a form
of therapy called "supportive-expressive therapy."[56]
Cost effectiveness
Aside
from the medical and psychological benefits, one of the most important
contributions of mind/body medicine is in reducing the costs of health
care by reducing the utilization rates of expensive inpatient and outpatient
services.
Other
studies have found reduced utilization rates for outpatient medical
services. For example, in one study 109 chronic pain patients took a 10-session
outpatient group mind/body program. A 36% reduction in total monthly clinic
visits for pain management was found in the first year after the program.[58]
Another
study looked at the medical care utilization rates of 2000 regular practitioners
of TM, comparing them with 600,000 other members of the same insurance
carrier. For children and young adults the reductions for inpatient services
were 50%, and for older adults it was 69%. The reductions for outpatient
services were 47% for children, 55% for young adults, and 74% for older
adults.
The
same pool of TM practitioners were compared to five other health insurance
pools, showing 55% fewer visits for benign or malignant tumors, 87% fewer
visits for heart disease, 30% fewer visits for infectious diseases, 31%
fewer visits for mental disorders, and 87% fewer visits for diseases of
the nervous system.[59]
STRENGTHS
AND LIMITATIONS
This
is obviously a complementary form of medicine rather than being a primary
treatment for major diseases. However, while it is usually thought of as
supportive rather than curative, there are obviously illnesses which do
not respond to conventional medical treatment and for which mind/body medicine
offers a way of gaining some relief and promoting recovery.
One
point of controversy that often arises in this tradition is the question
of whether its use implies an assumption that one's illness must have been
caused by the mind in the first place. For example, there are those who
question whether this approach should be applied to cancer because to use
it might suggest that the person "brought the cancer upon themselves."
This is an unnecessary assumption since the mind/body connection can be
exploited regardless of the cause of an illness.
The
leading PNI researcher Alastair Cunningham,
who holds Ph.D.'s in both psychology and immunology, articulates this point
well: "Although epidemiological considerations suggest that the contribution
of psychological factors to cancer onset is small... no upper limit to
what can be achieved by psychotherapy is necessarily thereby set: the relative
influence of the psyche on outcome may be greatly expanded by such therapy,
overriding the usual progression of disease."[60]
One
limitation is that the methods require an ability to sit quietly and, in
some cases, focus the mind on a technique. Some people suffering from extreme
symptoms of disease may at times have difficulty following through with
a routine of regular practice. Those who do best are able to sustain a
regular practice and achieve cumulative benefits over time.
"Clinical"
significance, on the other hand, means that actual medical benefits have
indeed been observed. The studies reporting a major change in the overall
course of an illness, or even longer survival time in cancer, provide the
best examples of clinically significant findings.
Hence,
a person may use mind/body techniques religiously and practice them perfectly,
with real commitment, and still not get the medical benefits they desire.
The degree of the contribution will vary from one person to the next, depending
in part on the severity of the illness.
When
people do not understand these limitations and have unrealistic expectations,
they are at risk of feelings of failure, self-blame, depression, or disappointment
that may arise when such expected results are not forthcoming. This is
called the "psychosocial morbidity" of mind/body medicine. Patients and
practitioners alike must endeavor to keep a realistic perspective on mind/body
medicine, not over-rating but also not under-rating it.
THE
PRACTITIONER-PATIENT RELATIONSHIP
Mind/body
techniques are often used in the context of psychotherapy or group therapy.
These situations offer the opportunity for addressing other important aspects
of coping with an illness. Often it is important to deal with the emotional
aspects of an illness before one can comfortably or confidently pursue
use of the mind/body techniques.
EVALUATING
PERSONAL RESULTS
The
results of mind/body techniques may be immediately apparent with changes
in mood, pain, or physiological state. This is one of the things that is
appealing about this tradition. The body gives direct feedback as to the
impact of the technique. In fact, the subjective experience is the most
important way of evaluating results.
This
is consistent with the advice of Carl Simonton, M.D. who first popularized
the use of imagery with cancer. According to Simonton, the criterion of
successful imagery practice is whether the person feels hopeful, powerful,
and optimistic after doing it. This is much more important than the details
of the images or whether they followed someone else's particular guidelines.[61]
Research has also confirmed that feeling confident in one's ability to
influence his or her health will in itself reduce the degree of stress
they feel and have its own health-promoting effects.
RELATIONSHIP
TO OTHER FORMS OF MEDICINE
Mind/body
medicine is usually used in the role of "complementary therapy." This means
it works along side other treatment in a supportive way. I like this term
because it communicates a cooperative partnership rather than being exclusive
of other traditions. In fact, all medical traditions now include within
them some attention to mind/body interactions and ways of working with
them.
COSTS
The
economics of mind/body medicine are another source of its appeal. There
are no inherent costs in using this tradition, other than for the individual
consultations or training programs one might engage to use this approach.
Many hospitals or community agencies offer group support programs that
are free of charge and that teach the techniques. There are also nonprofit
organizations such as the Centers for Attitudinal Healing and the Cancer
Support Community, both with nation-wide chapters, who offer free group
programs which include mind/body techniques.
There
are also many audiotape programs for home use that can be surprisingly
effective and inexpensive.
CHOOSING
A PRACTITIONER
Mind/body
medicine knows no disciplinary bounds. There are no standardized credentials
or requirements to use in evaluating one's preparation in these approaches.
Because most techniques are not very complicated anyway, what is probably
more important is that practitioner is competent in having a therapeutic
relationship, and also has a healthy regard for the limitations and appropriate
uses of mind/body techniques.
The
techniques themselves are usually quite familiar to anyone who is trained
in the mental health disciplines and other health care providers who received
mental health training. Many training programs in the mental health disciplines
include courses and experience in the field of behavioral medicine. Of
course, licensing by the state is usually a good place to start for any
such provider.
Most
but not all such programs of advanced certification require the practitioner
to be licensed in a professional discipline. A noteworthy exception in
this regard is hypnotherapy, which in many states is acknowledged as a
distinct profession without being linked to a specific academic discipline.
Some states limit the practice of hypnosis or hypnotherapy to licensed
therapists. Others allow it to be practiced by "lay hypnotists" but limit
the scope of problems that can be addressed.
Organizations
and Resources
The
Mind/Body Medical Institute, Division of Behavioral Medicine, New England
Deaconess Hospital
offers group mind/body programs for different illnesses. They also have
affiliate programs nationwide, and conduct clinical training several times
each year under the direction of Herbert Benson, M.D. and faculty. Address:
185 Pilgrim Road, Boston, Massachusetts 02215, phone (617)732-9525, FAX
(617)738-7023.
The
Cancer Support and Education Center
conducts retreats and group programs for people with cancer and other serious
illnesses. The program includes in-depth work with the emotional aspects
of illness, as well as imagery, movement, deep relaxation, breath therapy,
and nutrition. Address: 1035 Pine St., Menlo Park, California 94025, phone
(415)327-6166.
Stress
Reduction Clinic, University of Massachusetts Medical Center,
directed by Jon Kabat-Zinn, Ph.D., conducts
an eight-week program and a five-day residential program in mindfulness
training and stress reduction. Address: U.M.M.C., Worcester, Massachusetts
01655, phone (508)856-1616.
Insight
Meditation Society
and Insight Meditation West offer workshops and retreats nationwide
in mindfulness meditation, also called vipassana
meditation. Address: IMS, Pleasant St., Barre,
Massachusetts 01005, phone (508)355-4378. IMW, P.O. Box 909, Woodacre,
California 94973, phone (415)488-0164.
Maharishi Ayur-Ved
Products International
provides referrals to local resources for training in Transcendental Meditation
(TM). Address: 417 Bolton Road, Lancaster, Massachusetts 01523, phone (800)255-8332.
The
Academy for Guided Imagery
provides training for professionals in the use of guided imagery. Address:
P.O. Box 2070, Mill Valley, California 94942, phone (800)726-2070 or (415)389-9324,
FAX (415)389-9342.
Biofeedback
Certification Institute of America
provides a directory of certified biofeedback practitioners including their
background and experience. Address: 10200 W. 44th Avenue, Suite 304, Wheatridge,
Colorado 80033, phone (303)420-2902.
American
Chronic Pain Association
manages a list of over 500 support groups internationally, and publishes
workbooks and a newsletter. Address: P.O. Box 850, Rocklin, California
95677, phone (916)632-0922.
American
Council of Hypnotist Examiners (A.C.H.E.)
provides a referral list of professionally-trained hypnotists and hypnotherapists
certified by A.C.H.E. Does not require licensure in a health or mental
health profession. Address: 312 Riverdale Drive, Glendale, California 91204,
phone (818)242-5378.
Audiotape
Programs. A variety
of programs are available from the author for applying mind/body principles
to specific health concerns including: relaxation and stress reduction,
heart disease, hypertension, cancer, chronic fatigue syndrome, diabetes,
AIDS, autoimmune diseases, gastrointestinal disorders, pain control, and
preparation for surgery. Brochure address: William Collinge, Ph.D., P.O.
Box 2002, Sebastopol, California 95473, phone (800)745-1837.
Conclusion
Above
all, mind/body medicine is an approach that requires your own participation.
It does not require working with a practitioner, but if you choose to it
is important that you work with someone with whom you have a good rapport,
and whose style and manner you find comfortable. Often the practitioner's
voice alone is enough to either draw or repel some people.
Finally,
structured group programs have a lot of advantages over individual treatment.
If you can find a group program, you can gain a great deal of reinforcement
for healthful behavior change from the mutual support of others who share
the healing journey with you.
Eight
of the initial thirty studies funded by the Office of Alternative Medicine,
National Institutes of Health deal with mind/body medicine.
Biofeedback. Angele McGrady,
of the Medical College of Ohio, Toledo, is studying the use of biofeedback-assisted
relaxation in reducing the dosage of insulin required in type I insulin
dependent diabetes mellitus. The method is being studied as an alternative
to increasing dosage when the person is under stressful conditions. Richard
Sherman at Fitzsimmons Army Medical Center in Aurora, Colorado is evaluating
biofeedback in treating chronic musculoskeletal
low back pain and muscle-related orofacial
pain.
Imagery.
James Halper of Lenox Hill Hospital in New
York City is conducting a controlled study of the benefits of guided imagery
for patients with asthma.
Mary Jasnoski
of George Washington University, Washington, D.C. is examining the effects
of imagery on the immune system, with potential implications for use in
cancer and AIDS.
Blair
Justice of the University of Texas Health Sciences Center in Houston was
funded to conduct a controlled study examining the effects of a group imagery/relaxation
process on immune function and quality of life in breast cancer patients.
Jim
is a 46 year-old assembly line worker who received a disc injury in his
neck and developed a chronic pain syndrome involving head, neck, arm and
shoulder pain. He was referred by his physiatrist to Karen Carroll, a biofeedback
clinician practicing in Waterloo, Iowa, for pain control.
Carroll
used EMG, first for general muscular tension, and then for muscular tension
around the upper body and neck. Jim was able to discover a direct connection
between his thoughts, his level of nervous system arousal, muscular tension,
and eventually his pain level.
After
eight sessions, spaced progressively further apart and accompanied by home
practice of breathing exercises and progressive relaxation, his headaches
and neck pain completely disappeared. He was then able to use physical
therapy to further strengthen his neck and shoulders, and subsequently
returned to work. He stated, "I never really knew what it felt like to
relax, until now."
According
to Carroll, this case illustrates the benefits of commitment to self-regulation
and daily practice at home for someone who was motivated to avoid medication
and surgery if possible.
Alice,
suffering from chronic fatigue syndrome (CFS), undertook a two-week intensive
treatment of intravenous Acyclovir therapy
in the hospital. Acyclovir is a drug which
inhibits the reproduction of herpesviruses,
a family of viruses thought to be co-factors in CFS. One of the side effects
of this therapy is elevated blood pressure, which needs to be closely monitored.
Alice
was about half way through her treatment protocol when she enrolled in
a group mind/body medicine program. She brought her stainless steel drip
apparatus with her from the hospital, and stood it up beside her in the
circle with the other patients and their spouses.
The
first day involved a series of relaxation and deep breathing exercises.
The next day Alice returned to the group bubbling with excitement. She
reported that the previous evening her blood pressure had returned to normal.
The nursing staff were mystified, and wanted to know how she had done it.
Josephine,
36, suffering from headaches, sought help from her physician. Her blood
pressure was 150/100, she was twenty pounds overweight, and her cholesterol
level was 280 mg/dl. She smoked a pack a day and did not exercise regularly.
She was given a beta-blocker for high blood pressure, a cholesterol drug,
and was told to lose weight and stop smoking.
Two
months later her blood pressure was 160/102, she had lost no weight, had
not been able to stop smoking and her cholesterol was 290 mg/dl. When asked
why she hadn't cooperated with the recommendations she broke down in tears.
She hadn't been able to afford the medications ($90/month), her husband
had left her and their two children after a stormy and abusive marriage,
she had been trying to work two jobs, felt depressed, was not sleeping
well and her headaches were now a daily occurrence.
Before
leaving the program she outlined the situations which might be associated
with relapse and developed a plan for action which included returning periodically
for the drop-in groups for reinforcement. She also signed up for a SmokeEnders
group to start after the program ended.[62]
Larry
was a successful 42 year-old architect at the time he developed pancreatic
cancer with metastases in 1978. He integrated meditation and imagery into
his chemotherapy treatment, and though the road was long, he recovered
completely with no further signs of cancer three years later.
He
tells the following story about his devotion to doing his imagery practice:
"My
girlfriend at the time and I had taken a backpacking trip to the Grand Tetons.
This was nine months into my treatment. We'd get out there on the trail,
and after lunch, which was one of my times, I'd want to sit on the trail
or on a rock, or lean against a tree and do my visualization.
"This
woman was `go-go-go,' very achievement oriented. She was a very dynamic
and pushy and controlling person. `We're going to hike to this point, have
lunch... by such and such a time we'll be at the campground,' and she would
get terribly impatient with my after-lunch visualization.
"It
started leading to more and more friction, but I maintained my ground.
I was insistent that this is what I was going to do. By the time the trip
was over, we weren't speaking. We flew back from Wyoming, not even sitting
together on the plane, but that was very important for me, because I didn't
often put myself first when it came to her."
Heidi,
35, was scheduled for a round of chemotherapy for breast cancer. The treatment
was to take place on Friday, and she and her husband had tickets to fly
to Hawaii on Saturday for a week vacation.
As
is routine, she was called into the treatment center for a blood check
on the Monday before, to make sure her white cell count had recovered enough
from previous treatment to allow her to qualify for the next one. To her
shock, she was told that her white count was only about half what it should
be, and she would probably have to forego her vacation.
For
four days she practiced imagery intensively, several times a day, concentrating
on raising her white count. She used images of the bone marrow releasing
a steady, strong flow of white cells into her bloodstream, and spreading
throughout her body. She also imagined directing her breath into the bone
marrow, and thereby nourishing the stem cells (that produce the white cells)
so that they could grow and release more white cells.
On
that Friday, she went in for another blood test. Her white count had more
than doubled. She was able to have the treatment, and the next day was
able to walk on the beach with her husband.
Carol
Anne was scheduled to undergo a complicated abdominal surgery to remove
a cancerous tumor. Her surgeon told her that patients undergoing this procedure
typically lose ten to eleven units of blood.
For
several days prior to the surgery, Carol Anne practiced a form of imagery
in which she pictured her body going through the surgery without losing
any blood, the tissues knitting back together smoothly, no complications,
and a speedy recovery. She also imagined the look on the surgeon's face
when he realized that no blood had been lost.
The
day after the surgery, the surgeon came into her room and congratulated
her on how well she had come through the ordeal. To his amazement, she
had required only one unit of blood. When she told him of her preparations,
he smiled and walked out shaking his head.
Jeru,
a meditation teacher, came from a family with the hereditary condition
of polycystic kidney disease. At age 44
he began to have the typical symptoms of breakdown in kidney function,
and by age 63 he was on the waiting list to receive a kidney transplant.
He
was expecting a two-year wait and had already been using kidney dialysis
for ten months. However, a longtime student and devoted friend heard of
his need and immediately volunteered to donate a kidney to him.
Having
taught for many years how to understand and communicate with the subconscious, Jeru
developed his own plan to prepare his body to receive the foreign organ
and accept it easily without being rejected by his immune system. He used
meditation, inner dialogues with his subconscious, hypnosis, and affirmations
to help his body "welcome the kidney like a long-lost brother." His quick
recovery and the rapid rate at which his anti-rejection medication was
able to be reduced afterward led his physicians to regard him as a model
case.
According
to John Soos, Ph.D., a clinical psychologist
working with organ transplantations in Vancouver, Canada, the immune system
can indeed be taught to "improve its functioning against germs while
at the same time recognizing and tolerating the transplanted organ as an
integral part of the new body image."[63],[64]
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[26]. McClelland, D., and C. Kirshnit. The effect of motivational arousal through films on salivary immunoglobulin. Psychology and Health, 1988, 2:31-52.
[37]. Kiecolt-Glaser, J., R. Glaser, E. Strain, et. al. Modulation of cellular immunity in medical students. Journal of Behavioral Medicine, 1986, 9:311-20.
[59]. Orme-Johnson, D. Medical care utilization and the Transcendental Meditation program. Psychosomatic Medicine, 1987, 49:493-507.