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 Interviews with Nutritional Experts: How Vitamin E Prevents Heart Disease  
 
Interview with Dr. David Janero
   as interviewed by Richard A. Passwater PhD

1. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. Steinberg, D.L., et al. New England J. Med. 320:915-924 (1989).

2. Therapeutic potential of vitamin E in the pathogenesis of spontaneous atherosclerosis. Janero, D.R., Free Radical Biol. Med. 11:129-144 (1991).

3. Oxidative injury to myocardial membrane: direct modulation by endogenous alpha-tocopherol. Janero, D.R., et al. J. Mol. Cell. Cardiol. 21:1111-1124 (1989).

4. Hydrogen peroxide-induced oxidative stress to the mammalian heart-muscle cell (cardiomyocyte): lethal peroxidative membrane injury. Janero, D.R., et al. J. Cell. Physiol. 149:347-364 (1991).

5. Therapeutic potential of vitamin E against myocardial ischemic-reperfusion injury. Janero, D.R. Free Radical Biol. Med. 10:315-324 (1991).

6. Sequential assembly of very low density lipoprotein apolipoproteins, triacylglycerol, and phosphoglycerides by the intact liver cell. Janero, D.R. and Lane, M.D. J. Biol Chem. 258:14496-14504 (1983).

7. Free radical modification of low-density lipoprotein: mechanisms and biological consequences. Heinecke, J.W. Free Radical Biol. Med. 3:65-73 (1987).

8. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Janero, D.R. Free Radical Biol. Med. 9:515-540 (1990).

9. A receptor-mediated pathway for cholesterol homeostasis. Brown, M.S. and Goldstein, J.L. Science232:34-47 (1986).

10. Therapeutic potential of vitamin E in the pathogenesis of spontaneous atherosclerosis. Janero, D.R. Free Radical Biol.Med.11:129-144 (1991).

11. Protection of cardiac membrane phospholipid against oxidative injury by calcium antagonists. Janero, D.R., et al. Biochem. Pharmacol. 21:4197-4203 (1988).

12. Therapeutic potential of vitamin E against myocardial ischemic-reperfusion injury. Janero, D.R. Free Radical Biol. Med. 10:315-324 (1991).

All rights, including electronic and print media, to this article are copyrighted to © Richard A. Passwater, Ph.D. and Whole Foods magazine (WFC Inc.).

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 About The Author
Richard A. Passwater, Ph.D. has been a research biochemist since 1959. His first areas of research was in the development of pharmaceuticals and analytical chemistry. His laboratory research led to his discovery of......moreRichard Passwater PhD
 
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