Bottom Line? For those with CFS/FMS, unexplained fatigue, or breast symptoms, it is reasonable to take an iodine supplement (Iodoral) 1 a day for 1 bottle (90 days). After this, if you feel much better on it you can stay on it or stop to see if you still need it. You may find the one bottle is enough to "fill your tank" and correct any deficiencies, as the Energy Revitalization System vitamin powder supplies 150 mcg a day (the full RDA) for maintenance. For those with breast cancer, I would add the one Iodoral a day long term, and consider working with a holistic practitioner to take 5 a day while waiting for the research to be done.