Join Now!      Login

Whole Person Wellness Program
 
healthy.net Wellness Model
Skip Navigation Links
 
 
FREE NEWSLETTER
   
   
   
 
Health Centers
Key Services
 
America's Worst Enemy?
What is the leading cause of death in the United States?
Cancer
Auto Accidents
Heart Disease
Perscription Meds

 
 

 Diabetes: Epidemic by Prescription 
 
The following is one in an ongoing series of columns entitled What Doctors Don't Tell You by . View all columns in series
Dr Lisa Landymore-Lim, a British chemist specializing in immunology and biomedical chemistry, became curious about the explosion of childhood illnesses such as asthma and diabetes, and carried out a pilot study of drug-prescribing among juvenile diabetics. In 1994, WDDTY published her initial findings. Here is her evidence for suggesting a link between the excessive use of antibiotics and diabetes.

Cases of chemicals and drugs causing temporary and permanent insulin-dependent diabetes (IDD) are well documented in the medical literature (Pharmacol Rev, 1970; 2: 485-518; J Rheumatol, 1987; 14: 732-5). Unfortunately, such cases don't usually come to the attention of physicians, and most patients are completely unaware of these potential hazards.

Two of the best-known chemicals capable of damaging pancreatic beta cells-responsible for the production of insulin-are the antibiotic streptozocin (Zanosar®, also used in chemotherapy) and the chemical alloxan. These drugs are routinely used in animal experiments to study diabetes. Vacor, a rat poison, has also been reported to cause the disease.

There is a structural similarity between the chemicals streptozocin, alloxan and Vacor: in each, there is at least one oxygen atom joined by two bonds to a carbon atom (C=O), forming a carbonyl group, which is flanked on each side by a nitrogen (N) atom.

This is of interest because carbonyl groups and nitrogen atoms can be considered reactive species due to their excess of negative charge. This means that they are electron-rich and, thus, have an affinity for positively charged species such as zinc ions (Zn2+). Thus, they behave like magnets, attracting oppositely charged species.

Insulin is stored in the pancreas together with zinc. In fact, the pancreas has the highest concentration of zinc in the body, making it potentially a major target for chemical attack.

In addition, double-bonded oxygen groups are also potential sources for the formation of free radicals, those destructive agents that have been implicated in the onset of cancer.

Other chemicals known to be capable of producing diabetes in humans include the drugs dapsone, used in the treatment of leprosy, and pentamidine isethionate, an anti-protozoal agent used to treat pneumonia in AIDS patients.

However, dapsone and pentamidine bear little structural resemblance to streptozocin and alloxan, except that dapsone does contain electronegatively charged oxygen atoms that are double-bonded to sulphur (instead of carbon). Both drugs also have electronegative terminal amino (NH2) groups attached to, or in close proximity of, a benzene ring.

Nevertheless, comparison of daps-one and pentamidine with the drugs frusemide and chlorthiazide, diuretics reportedly associated with the onset of diabetes, also reveals structural similarities. In frusemide, once again we see the electronegative sulphonyl (S=O) group and a terminal amino (NH2) group, whereas chlorthiazide has two SO2 groups and a terminal NH2.

Such groups are not commonly found in drugs. In the American Hospital Formulary Service Drug Information database, which lists some 1000 drugs, less than 5 per cent have either an amino group or a carbon atom bound to a benzene ring.

Sulphonyl groups, however, are commonly found in thiazide diuretics and sulphonamide drugs. Alarmingly, in Australia, diuretics like hydrochlorthiazide (identical to chlorthiazide except for an additional hydrogen atom) are given to young women to treat premenstrual water retention.

   CONTINUED    1  2  3  4  5  Next   
 Comments Add your comment 

 About The Author
What Doctors Don’t Tell You is one of the few publications in the world that can justifiably claim to solve people's health problems - and even save lives. Our monthly newsletter gives you the facts you won't......moreWhat Doctors Don't Tell You
 
 From Our Friends
 
 
 
Popular & Related Products
 
Popular & Featured Events
Integrative Healthcare Symposium 2015
     February 19-21, 2015
     New York, NY USA
 
Wellness Inventory Certification Training (Level I)
     February 24-May 26, 2015
     Teleclass, CA USA
 
Additional Calendar Links
 
Stevia Products & Info
 
Dimensions of Wellness
Wellness, Self Responsibility, Love, dimension!

Home       Wellness       Health A-Z       Alternative Therapies       Find a Practitioner       Healthy Products       Bookstore       Wellness Inventory
Healthy Kitchen       Healthy Woman       Healthy Man       Healthy Child       Healthy Aging       Wellness Center       Nutrition Center       Fitness Center
Free Newsletter      What Doctor's Don't Tell You      Stevia.com      Discount Lab Tests      First Aid      Global Health Calendar      Privacy Policy     Contact Us
Disclaimer: The information provided on HealthWorld Online is for educational purposes only and IS NOT intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek professional medical advice from your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.
Are you ready to embark on a personal wellness journey with our whole person approach?
Learn More/Subscribe
Are you looking to create or enhance a culture of wellness in your organization?
Learn More
Do you want to become a wellness coach?
Learn More
Free Webinar