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Physical Activity as a Metabolic Stressor

© Edward F. Coyle PhD

Overview
It is becoming increasingly clear that a person's health and well-being are improved by physical activity as well as by a nutritious diet. Both physical activity and diet stimulate processes that, over time, alter the morphological composition and biochemical function of the body. Physical activity and diet are interrelated in that optimal adaptation to the stress of exercise-training usually requires a diet that is not lacking in various nutrients. Physical activity should therefore be viewed as providing stimuli that stress various systems of the body to differing degrees depending upon the type and intensity of exercise. Furthermore, the progressive adaptations to regular physical activity are very specific in response to the stress encountered during physical activity.

Definitions

  • Physical activity is defined as "any bodily movement produced by the contraction of skeletal muscle." 1
  • Exercise, a type of physical activity, is defined as "a planned, structured, and repetitive bodily movement done to improve or maintain one or more components of physical fitness."'
  • Physical fitness is defined as "a set of attributes that people have or acquire that relates to their ability to perform physical activity.""
  • Dietary supplementsin the United States are usually defined as comprising plant extracts, enzymes, vitamins, minerals, and hormonal products that are available without prescription and are consumed in addition to the regular diet. In the present context, the addition of macronutrients and water to the diet can also be viewed as supplements.

Stress of Physical Activity
As shown in Figure 1, physical activity increases metabolism in the active muscles and other cells, and in the process of muscle contraction, produces mechanical loading. These processes of altered metabolism and mechanical loading are key physiological stimuli that serve to alter protein synthesis and degradation. This forms the basic scheme by which the body produces specific adaptations to exercise training and thus develops physical fitness. Substrates, obtained from the diet or endogenous production, supply the energy for metabolism and work and also provide the amino acids for protein synthesis. These processes are typically regulated by enzymatic activity requiring certain co-factors. Furthermore, all the steps shown are influenced by humoral factors as well as other effects.

                   FIGURE 1.

The stress of physical activity is typically categorized in two ways: (1) by the metabolic aerobic stress it places on the cardiovascular system when exercise is performed for several minutes or longs (Table 1) and (2) by the percentage of the individual's one-repetition maximum (1RM) for physical activity involving lifting weights for short periods of time (Table 2). Weightlifting is largely power by anaerobic metabolism.

TABLE 1. Classification of Intensity of Aerobic Exercise1

           Relative Intensity                  Absolute Intensity in METSa
Classification     % Max Heart Rate     %Max VO2 or
 % Heart Rate Reserve  
   RPEb  Young
20-29 years
Old
60-75 years


Very Low <30 <25 <10<3.0<2.0
Low 30-49 25-39 10-11 3.0- 4.7 2.0- 3.1
Moderate 50-69 40-59 12-13 4.8- 7.1 3.2- 4.7
High 70-89 60-85 14-15 7.20- 10.1 4.8- 6.7
Very High > or = 90 > or = 85 > or = 16 > or = 10.2 > or = 6.8
Maximumc 100 100 20 12.0 8.0

aAbsolute intensity, measured in metabolic equivalent units (METS), is an appropriate mean value for men.
Mean values for women are approxiamately 1-2 METS lower than those for men.
bBorg Rating of Perceived Exertion-original 7-20 scale. 
cMaximum values are mean values during maximal exsercises for healthy adults.
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