Join Now!      Login

Whole Person Wellness Program Wellness Model
Skip Navigation Links
Health Centers
Key Services
Medicial Mistakes?
How many people each year suffer some type of preventable harm that contributes to their death after a hospital visit?
from 46,000 to 78,000
from 78,000 to 132,000
from 132,000 to 210,000
from 210,000 to 440,000

 What Doctors Don't Tell You: New drugs: New profits for old product - Guinea pigs are we 
What Doctors Don't Tell You © (Volume 13, Issue 4)
Often, the short-term clinical trials, which also often involve only small numbers of ‘healthy’ patients don’t uncover the worst side-effects, which then only emerge when a drug is taken by the public at large. Sometimes patients even die before a drug is withdrawn, as happened with Lotronex (alosetron), a drug to treat irritable bowel syndrome (IBS) in women. Lotronex had a shelf life of just nine months before it was withdrawn from the market.

The drug was approved for use in America by the drug regulator, the Food and Drug Administration (FDA), on the basis of two 12-week trials that involved 1273 women. Overall, the drug was found to be far more effective than a placebo (sugar pill).

However, researchers had noted that four cases of colitis were reported during the trials, but each case was short-lasting, mild and reversible once the drug treatment was stopped.

But soon after the drug was approved in February 2000, the FDA started receiving reports of more serious reactions of intestinal damage and ruptured bowels. The first cases were received within weeks of the approval being granted and, by November, the FDA had 70 cases of serious adverse events, including three deaths.

It’s interesting to note that even faced with this overwhelming evidence, the FDA did not withdraw the drug’s licence. The drug’s manufacturer, however, decided to withdraw the drug from the market as the possibility of lawsuits started to loom.

 Comments Add your comment 

 About The Author
What Doctors Don't Tell You What Doctors Don’t Tell You is one of the few publications in the world that can justifiably claim to solve people's health problems - and even save lives. Our monthly newsletter gives you the facts you won't......more
 From Our Friends
Popular & Related Products
Popular & Featured Events
Error Reading Event Calendar
Stevia Products & Info
Dimensions of Wellness
Wellness, Finding Meaning, dimension!

Home       Wellness       Health A-Z       Alternative Therapies       Find a Practitioner       Wellness Inventory
Healthy Kitchen       Healthy Woman       Healthy Man       Healthy Child       Healthy Aging       Wellness Center       Nutrition Center       Fitness Center
Stevia      Discount Lab Tests      First Aid      Global Health Calendar      Healthy Products       Privacy Policy     Contact Us
Disclaimer: The information provided on HealthWorld Online is for educational purposes only and IS NOT intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek professional medical advice from your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.
Are you ready to embark on a personal wellness journey with our whole person approach?
Learn More/Subscribe
Are you looking to create or enhance a culture of wellness in your organization?
Learn More
Do you want to become a wellness coach?
Learn More
Free Webinar