But what of the people previously
treated with EDTA back in 1959?
Only one of the 47 people
in that group had developed cancer. The cancer rate in people
in the contaminated area who had not received EDTA was 600 per
cent above that of the group who had had chelation.
Far and away the best protection
from lead toxicity and its longterm effects is to avoid
it altogether. However, this is of course not always within the
control of the individual and a second best bet is to have the
lead removed via chelation as a protective measure against its
undoubted toxicity which can contribute towards the evolution
Australian research scientist
John Sterling, who has worked at the famous Issels clinic in Germany,
mentions in a personal communication that Issels had noted a marked
protective effect against cancer after use of EDTA chelation.
Animal studies (using mice)
have shown that intravenous EDTA plays a preventive role against
cancer, largely, it is thought, through removal of metallic ions
which seem to be essential for tumour growth.
Walker and Gordon believe
that the prevention offered to the citizens of Zurich was partly
as a result of removal of metal ions and of lead (which can chronically
depress immune function) and also due to the improvement in circulation
which chelation produced. Tumours flourish in areas of poor oxygenation
and the increase in the levels of this which chelation allows
would, they believe, be sufficient to retard cancer development.
Halstead (1979) points to
the significant increase in metal ions found as tissues age and
the increased likelihood of cancer developing. There is also a
proven link between high levels of certain metals in topsoil and
cancer in the same regions. Interestingly, he confirms that most
forms of chemotherapy involve drugs which have chelating effects
either directly or as a result of breakdown of their constituents.
He quotes experimental studies which show that in some forms of
cancer such as Ehrlich's ascites tumour the use of EDTA was significantly
able to strip the tumour cells of their heavy protective coat,
allowing other mechanisms (such as protein digesting enzymes)
to destroy the tumours.
At the very least EDTA chelation
can be seen to offer a useful line of investigation in cancer
prevention, and possibly treatment, in some forms of this disease.
Benefits for some
Dr Wayne Perry (1988) comments
on one of the beneficial 'side effects' of EDTA therapy when he
states: 'Those who have used EDTA have been impressed by the dramatic
effects that can occur in some patients, and this action might
be explained by its powerful antidepressant effect, shown
in a double blind trial over and above any placebo action' (See
Kay et al 1984.) In discussing the objective evidence of general improvement amongst
patients having EDTA he includes 'general alertness, concentration
and memory' as common.
Clearly, if circulation to
the brain is enhanced the function of that organ should improve.
Equally important to mental function would be the removal of heavy
metals, the toxicity of which are common causes of a wide range
of problems affecting the brain and nervous system. It should
therefore not be surprising that EDTA often leads to improved
memory and reduced tendency to depression and other apparently
The research team of McDonagh,
Rudolph and Cheraskin have looked at just this aspect of EDTA
chelation therapy's effect the psychotherapeutic benefits.
(McDonagh, Rudolph and Cheraskin, 1984, 1985a, 1985b) They used
a standard medical questionnaire (Cornell Medical Index
see Brodman et al 1949) at the first
consultation to allow 139 routine privatepractice patients,
83 of whom were male, to answer questions from which 'depression
'tension' and 'anger' tendencies could be discovered. These same
patients completed the same questionnaire at the end of a series
of EDTA infusions (plus multimineral/vitamin support supplementation)
over a two month period. There was a 40 per cent reduction in
depression indications amongst those patients who showed a tendency
towards depression in their first questionnaire. There was a 50
per cent reduction in 'tension' symptoms and a 46 per cent reduction
in 'anger' indications at the end of the treatment period.
The researchers speculate
that the improvement was due to overall improvement in cellular
nutrition as a result of the enhanced circulation due to this
form of treatment. They note that the improvements in emotional
status, observed in this study, were superior in degree to any
physical improvements noted in their many previous studies.
and fatigue reduced after EDTA therapy
Using the same approach these
researchers had over 100 patients complete the whole Cornell Medical
Index (CMI) questionnaire before and after a chelation series
which averaged 26 infusions over a twomonth period. The
CMI questionnaire is designed to collect a great deal of information
in a short space of time. Anyone with more than 25 positive answers
out of the 195 questions is considered to be suffering from a
significant degree of current illhealth.
Before treatment, the average
number of positive answers amongst these patients was 31.7, indicating
an overall poor level of health. Some patients had as many as
95 'Yes' answers, with the lowest score being 3; more than half
of the patients had over 25 positive answers. When the CMI questionnaire
was answered again after the therapy series there was a drop of
46 per cent in those with more than 25 positive answers and the
overall number of symptoms reported dropped by 15 per cent.
The CMI is divided into different
sections and when these were analysed for beforeandafter
changes, the pattern that emerged was as follows:
Musculoskeletal symptoms declined
by 25 per cent; neurological symptoms by 19 per cent; cardiovascular
by 19 per cent; skin conditions by 18 per cent; respiratory by
17 per cent; genital by 13 per cent; gastrointestinal by
11 per cent and urinary by 11 per cent.
Specific attention was paid
to fatigue in these patients, as this general symptom is amongst
the commonest and most worrying for many people in poor health.
Seven questions in the CMI relate specifically to the degree of
fatigue/tiredness felt. The percentage of those answering this
section who had no fatigue symptoms rose from 31 per cent to 56
per cent over the course of the treatment series, and of those
originally reporting fatigue as a symptom, fully 39 per cent showed
an appreciable improvement. Since most researchers and therapists
involved in chelation therapy report that the greatest beneficial
effect is not felt until up to 90 days after the cessation of
therapy, these results may well indicate only the beginning of
the benefits ultimately achieved.
Considering the fact that
over half those involved were by any definition in very poor health,
the improvements were remarkable, and the very general nature
of their spread supports the contention of these researchers that
they were due to generalized nutritional enhancement due to circulatory
improvements resulting from EDTA therapy.