Skip Navigation Links
 



                     


 



   
    Learn More     Subscribe    
Join Now!      Login
 
 
 
FREE HEALTH
NEWSLETTER
 
 
Vitamin D Poll
Are you currently taking a Vitamin D supplement?
 
 
 
 
W
hat Doctors Don't Tell You
 

DIABETES
THE SCANDAL OF HUMAN INSULIN

© What Doctors Don't Tell You (Volume 11, Issue 8)

Surgical treatments

The saga of animal versus 'human' insulin overshadows the fact that new frontiers in the treatment of IDDM have been incredibly slow to manifest.

Some prominent researchers have begun pursuing and promoting surgical solutions, such as pancreas transplants and, more recently, islet (beta cell) transplantation. Neither option has proven itself to be a reasonable option for the majority of suffers (J Mol Med, 1999; 77: 148-52; Transpl Proc, 1998; 30: 1940-3. Transplantation of the pancreas is expensive and has a low success rate. Often, this invasive operation is reserved for those whose conditions have deteriorated to the extent that they have nothing much to lose by opting for surgery. However, with a failure rate of 20-25 per cent (Transplant Proc, 1992; 24: 762-6), those not in this category might consider it too much of a gamble.

Islet transplantation is a less invasive operation, but its success rate is even lower. Of the 267 islet transplants that have taken place in the last 10 years, only 12.4 per cent have resulted in insulin independence for periods of more than one week, and only 8.2 per cent have resulted in insulin independence for periods of more than one year (Brendel M et al, International Islet Transplant Registry Report, University of Giessen, 1999: 1-20). As it appears that more than one donor pancreas is required per recipient (after processing to isolate the islets, which are then transplanted in a suspension via the portal vein), there are simply not enough donors, either animal or human, to supply the close to one million islets needed per patient (N Engl J Med, 2000; 343: 230-8).

In both types of transplants, finding ways to avoid rejection is difficult. Even if the grafts are successful, the diabetic patient may switch from a lifetime of insulin to a lifetime of immunosuppressive drugs, which bring a higher risk of cancer and infection.

Islet regeneration

Type I diabetes is caused by an autoimmune reaction directed against the insulin producing beta cells in the pancreas. From birth and, some would argue, before birth these cells begin to die off in a future diabetic until the individual, usually before the age of 30, is left with no means of producing the insulin needed to transport glucose to the cells of the body. In such persons, the body literally starves to death, devoid of the energy from glucose to carry out normal functions.

The big question is, given the right conditions, are islets capable of regeneration? Many scientists believe they are at least, theoretically. There is, for instance, a dramatic natural increase in the number of islets in women during pregnancy (J Mol Med, 1999; 77: 62-6). This regeneration appears to be moderated by hormones such as prolactin, which target the beta cells and cause them to proliferate. Also, through various means, scientists have managed to regenerate islets using animal models (Diabetes, 1988; 37: 334-41; Pancreas, 2000; 21: 63-8). But the human research is simply not there. What is also missing is concrete information on what causes this autoimmune response, and how it can be corrected so that the process of beta cell destruction is not repeated.

Alternative treatments

The majority of research into IDDM is very conventional, focused on drugs, surgery and genetic medicine. However, in 1980, in an effort to widen the scope of diabetes research, the World Health Organization requested that researchers reexamine traditional medicines. Prior to 1922, diabetes was managed exclusively with botanical medicine and it was hoped that, by looking at traditional methods of managing diabetes, a way to lower patients' reliance on insulin might be found.

Add your comment   CONTINUED      Previous   1  2  3  4  5  Next   
About The Author
What Doctors Don’t Tell You is one of the few publications in the world that can justifiably claim to solve people's health problems - and even save lives. Our monthly newsletter gives you the facts you won't read anywhere else about what works, what doesn't work and what may harm you in both orthodox and alternative medicine. We'll also tell you how you can prevent illness.......more
Related Articles
 
Share   Facebook   Buzz   Delicious   Digg   Twitter  
 
 
 
 
 
 
From Our Sponsor
 
 
 
 
 
 
Featured Events
Wellness Inventory Certification Training - Level I
     February 18-May 20, 2014
     Los Angeles, CA USA
 
Additional Calendar Links
 
Wellness, Sensing, dimension!

Search   
Home       Wellness       Health A-Z       Alternative Therapies       Find a Practitioner       Healthy Products       Bookstore       Wellness Inventory
Healthy Kitchen       Healthy Woman       Healthy Man       Healthy Child       Healthy Aging       Wellness Center       Nutrition Center       Fitness Center
Free Newsletter      What Doctor's Don't Tell You      Stevia.com      Discount Lab Tests      First Aid      Global Health Calendar      Privacy Policy     Contact Us

Disclaimer: The information provided on HealthWorld Online is for educational purposes only and IS NOT intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek professional medical advice from your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.