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 Acupuncture Usage - Biochemistry and Physiology: Current Bibliographies in Medicine: Acupuncture Usage - Biochemistry and Physiology 
National Institutes of Health ©
Selected Controlled Trials

Alavi A, LaRiccia P, Sadek AH, Newburg AB, Lee L, Reich H, et al. Progress report: SPECT scan imaging of the brain before and after acupuncture [abstract]. Acupunct Electrother Res 1997;22(1):68.

Ceccherelli F, Gagliardi G, Matterazzo G, Visentin R, Giron G. The role of manual acupuncture and morphine administration on the modulation of capsaicin-induced edema in rat paw. A blind controlled study. Acupunct Electrother Res 1996 Jan-Mar;21(1):7-14.

Cheng N, Van Hoof H, Bockx E, Hoogmartens MJ, Mulier JC, De Dijcker FJ, Sansen WM, De Loecker W. The effects of electric currents on ATP generation, protein synthesis, and membrane transport in rat skin. Clin Orthop 1982 Nov-Dec;(171):264-72.

Ernst M, Lee MH. Influence of naloxone on electro-acupuncture analgesia using an experimental dental pain test. Review of possible mechanisms of action. Acupunct Electrother Res 1987;12(1):5-22.

Fei H, Xie GX, Han JS. Low and high frequency electroacupuncture stimulation releases Met-5 enkephalin and dynorphin A and B in rat spinal cord. Chin Sci Bull 1987;32:1496-501.

Gagliardi G, Ceccherelli F, Visentin R, Matterazzo G, Giron G. Ripercussioni della paraclorofenilalanina e del naloxone sulla modulazione agopunturale dell'infiammazione neurogena. G Ital Riflessoter Agopunt 1995;7(1):17-23. (Ita).

Han JS. Molecular events underlying the anti-opioid effect of CCK-8 in the CNS. In: Cuello AC, Collier B, editors. Pharmacological sciences: perspectives for research and therapy in the late 1990's. Basel: Birkhauser; c1995. p. 199-207.

Han JS, Chou PH, Lu CC, Yang TH, Jen MF. The role of central 5-HT in acupuncture analgesia. Sci Sin 1979 Jan;22(1):91-104.

Han JS, Ding XZ, Fan SG. Cholecystokinin octapeptide (CCK-8): antagonism on electroacupuncture analgesia and a possible role in electroacupuncture tolerance. Pain 1986 Oct;27(1):101-15.

Han JS, Li SJ, Tang J. Tolerance to electroacupuncture and its cross tolerance to morphine. Neuropharmacology 1981 Jun;20(6):593-6.

Han JS, Terenius L. Neurochemical basis of acupuncture analgesia. Annu Rev Pharmacol Toxicol 1982;22:193-220.

Han JS, Wang Q. Mobilization of specific neuropeptides by peripheral stimulation of identified frequencies. News Physiol Sci 1992 Aug;7:176-80.

Han JS, Xie GX, Zhou ZF, Folkesson R, Terenius L. Enkephalin and beta-endorphin as mediators of electro-acupuncture analgesia in rabbits: an antiserum microinjection study. Adv Biochem Pharmacol 1982;33:369-77.

Mayer DJ, Price DD, Rafii A. Antagonism of acupuncture analgesia in man by the narcotic antagonist naloxone. Brain Res 1977;121(2):368-72.

Pert CB, Snyder SH. Opiate receptor: demonstration in nervous tissue. Science 1973 Mar 9;179(77):1011-4.

Pomeranz B, Chiu D. Naloxone blockade of acupuncture analgesia: endorphin implicated. Life Sci 1976 Dec 1;19(11):1757-62.

Sjolund BH, Eriksson MB. The influence of naloxone on analgesia produced by peripheral conditioning stimulation. Brain Res 1979 Sep 14;173(2):295-301.

Tang NM, Dong HW, Wang XM, Tsui ZC, Han JS. Cholecystokinin antisense RNA increases the analgesic effect induced by electroacupuncture or low dose morphine: conversion of low responder rats into high responders. Pain 1997 May;71(1):71-80.

Wu CC, Chen MF, Lin CC. Absorption of subcutaneous injection of Tc-99m pertechnetate via acupuncture points and non-acupuncture points. Am J Chin Med 1994;22(2):111-8. Comment in: Am J Chin Med 1996;24(1):101-2.

Xie CW, Tang J, Han JS. Central norepinephrine in acupuncture analgesia: differential effects in brain and spinal cord. In: Takagi H, Simon EJ, editors. Advances in endogenous and exogenous opioids. Proceedings of the International Narcotic Research Conference (Satellite Symposium of the 8th International Congress of Pharmacology); 1981 Jul 26-30; Kyoto, Japan. Tokyo: Kodansha; 1981. p. 288-90.

Xu W, Qiu XC, Han JS. Serotonin receptor subtypes in spinal antinociception in the rat. J Pharmacol Exp Ther 1994 Jun;269(3):1182-9.

Yi G, Xu T, Jinsheng C, Chunxu Z, Ping J. Experimental study of the acupuncture effects on calcium ion concentration in rabbits' acupoints. World J Acupunct Moxibustion 1992 Dec;2(4):51-4.

Yu YH, Gao M, He LF. [Time course of alterations of proopiomelanocortin mRNA level in rat hypothalamic arcuate nucleus following electroacupuncture]. Shang Hai I Ko Ta Hsueh Hsueh Pao 1994;21 Suppl:60-3. (Chi).

Zadina JE, Hackler L, Ge LJ, Kastin AJ. A potent and selective endogenous agonist for the mu-opiate receptor. Nature 1997 Apr 3;386(6624):499-502. Comment in: Nature 1997 Apr 3;386(6624):442.

Zhu CB, Jin L, Xu SF. Accelerated release of enkephalin and endorphin in rat brain by droperidol during electroacupuncture analgesia. Chin J Physiol Sci 1995;11(2):123-8.

Zhu CB, Li XY, Zhu YH, Xu SF. Binding sites of mu receptor increased when acupuncture analgesia was enhanced by droperidol: an autoradiographic study. Chung Kuo Yao Li Hsueh Pao 1995 Jul;16(4):311-4.

Other Data

Abad-Alegria F, Adelantado S, Martinez T. The role of the cerebral cortex in acupuncture modulation of the somesthetic afferent. Am J Chin Med 1995;23(1):11-4.

Abad-Alegria F, Galve JA, Martinez T. Changes of cerebral endogenous evoked potentials by acupuncture stimulation: a P300 study. Am J Chin Med 1995;23(2):115-9.

Abbate D, Santamaria A, Brambilla A, Panerai AE, Di Giulio AM. Beta-endorphin and electroacupuncture [letter]. Lancet 1980 Dec 13;2(8207):1309.

Aso T, Motohashi T, Murata M, Nishimura T, Kakizaki K. The influence of acupuncture stimulation on plasma levels of LH, FSH, progesterone and estradiol in normally ovulating women. Am J Chin Med 1976;4(4):391-401.

Bensoussan A. Part 1: Acupuncture meridians - myth or reality? Complement Ther Med 1994;2(1):21-6.

Bensoussan A. Part 2: Acupuncture meridians - myth or reality? Complement Ther Med 1994;2(2):80-5.

Bian JT, Sun MZ, Xu MY, Han JS. Antagonism by CCK-8 of the antinociceptive effect of electroacupuncture on pain-related neurons in nucleus parafascicularis of the rat. Asia Pac J Pharmacol 1993;8(2):89-97.

Bing Z, Cesselin F, Bourgoin S, Clot AM, Hamon M, Le Bars D. Acupuncture-like stimulation induces a heterosegmental release of Met-enkephalin-like material in the rat spinal cord. Pain 1991;47(1):71-7.

Bing Z, Villanueva L, Le Bars D. Acupuncture-evoked responses of subnucleus reticularis dorsalis neurons in the rat medulla. Neuroscience 1991;44(3):693-703.

Bishop B. Pain: its physiology and rationale for management. Part III. Consequences of current concepts of pain mechanisms related to pain management. Phys Ther 1980;60(1):24-37.

Bossut DF, Huang ZS, Sun SL, Mayer DJ. Electroacupuncture in rats: evidence for naloxone and naltrexone potentiation of analgesia. Brain Res 1991 May 17;549(1):36-46.

Bossut DF, Mayer DJ. Electroacupuncture analgesia in naive rats: effects of brainstem and spinal cord lesions, and role of pituitary-adrenal axis. Brain Res 1991 May 17;549(1):52-8.

Bossut DF, Mayer DJ. Electroacupuncture analgesia in rats: naltrexone antagonism is dependent on previous exposure. Brain Res 1991 May 17;549(1):47-51.

Bragin EO, Malygina SI, Zharova TV, Erygina EG. [Functional changes in the pituitary-adrenal system during the action of electroacupuncture on patients with spinal osteochondrosis]. Vopr Kurortol Fizioter Lech Fiz Kult 1989 May-Jun;(3):40-4. (Rus).

Bragin EO, Popkova EV, Vasilenko GF. [Effects of repeated acupuncture action on pain sensitivity and beta-endorphin contents of the hypothalamus and midbrain of the rat]. Biull Eksp Biol Med 1989 Jan;107(1):59-61. (Rus).

Bragin EO, Vasilenko GF, Batueva NN, Belitskaia RA, Shumova OV. [The role of catecholaminergic group-A5 neurons in analgesia induced by auricular electroacupuncture and in electrodermal pain stimulation]. Biull Eksp Biol Med 1989 Mar;107(3):310-2. (Rus).

Bucinskaite V, Lundeberg T, Stenfors C, Ekblom A, Dahlin L, Theodorsson E. Effects of electro-acupuncture and physical exercise on regional concentrations of neuropeptides in rat brain. Brain Res 1994 Dec 12;666(1):128-32.

Bucinskaite V, Theodorsson E, Crumpton K, Stenfors C, Ekblom A, Lundeberg T. Effects of repeated sensory stimulation (electro-acupuncture) and physical exercise (running) on open-field behaviour and concentrations of neuropeptides in the hippocampus in WKY and SHR rats. Eur J Neurosci 1996;8(2):382-7.

Cao XD, Xu SF, Lu WX. Inhibition of sympathetic nervous system by acupuncture. Acupunct Electrother Res 1983;8(1):25-35.

Chakrabarti S, Ganguly A, Poddar MK. Diazepam: effect on multiple electroacupuncture-induced changes in regional GABA of mammalian central nervous system. Methods Find Exp Clin Pharmacol 1991;13(3):167-73.

Chakrabarti S, Poddar MK. Effect of electroacupuncture on the long-term diazepam-induced changes in regional GABA of mammalian central nervous system. Methods Find Exp Clin Pharmacol 1992;14(2):115-23.

Chang CL, Lee JC, Tseng CC, Chang YH, Cheng JT. Decrease of anesthetics activity by electroacupuncture on Jen-Chung point in rabbits. Neurosci Lett 1995;202(1-2):93-6.

Chang YH, Hsieh MT, Cheng JT. Increase of locomotor activity by acupuncture on Bai-Hui point in rats. Neurosci Lett 1996;211(2):121-4.

Chen BY, He L. Electroacupuncture enhances activity of adrenal nucleolar organizer regions in ovariectomized rats. Acupunct Electrother Res 1992;17(1):15-20.

Chen BY, Yu J. Relationship between blood radioimmunoreactive beta-endorphin and hand skin temperature during the electro-acupuncture induction of ovulation. Acupunct Electrother Res 1991;16(1-2):1-5.

Chen GB, Li SC, Jiang CC. Clinical studies on neurophysiological and biochemical basis of acupuncture analgesia. Am J Chin Med 1986;14(1-2):84-95.

Chen GS, Erdmann W. Effects of acupuncture on tissue-oxygenation of the rat brain. Comp Med East West 1977;5(2):147-54.

Chen KG. II. Electrical properties of meridians: with an overview of the electrodermal screening test. IEEE Eng Med Biol Mag 1996;15(3):58-63.

Chen KG. III. Applying quantum interference to EDST medicine testing. IEEE Eng Med Biol Mag 1996;15(3):64-6.

Chen MF, Wu CC, Jong SB, Lin CC. Differences in acupuncture point SP-10 and non-acupuncture point following subcutaneous injection of Tc-99m pertechnetate. Am J Chin Med 1993;21(3-4):221-9.

Chen XH, Geller EB, Adler MW. Cholecystokinin-octapeptide microinjected into the periaqueductal grey antagonizes analgesia induced by peripheral electroacupuncture stimulation in rats. Regul Pept 1994;54(1):55-6.

Chen XH, Geller EB, Adler MW. Electrical stimulation at traditional acupuncture sites in periphery produces brain opioid-receptor-mediated antinociception in rats. J Pharmacol Exp Ther 1996;277(2):654-60.

Chen XH, Guo SF, Chang CG, Han JS. Optimal conditions for eliciting maximal electroacupuncture analgesia with dense-and-disperse mode stimulation. Am J Acupunct 1994;22(1):47-53.

Chen XH, Han JS. All three types of opioid receptors in the spinal cord are important for 2/15 Hz electroacupuncture analgesia. Eur J Pharmacol 1992;211(2):203-10.

Chen XH, Han JS. Analgesia induced by electroacupuncture of different frequencies is mediated by different types of opioid receptors: another cross-tolerance study. Behav Brain Res 1992;47(2):143-9.

Chen XH, Han JS, Huang LT. CCK receptor antagonist L-365,260 potentiated electroacupuncture analgesia in Wistar rats but not in audiogenic epileptic rats. Chin Med J (Engl) 1994 Feb;107(2):113-8.

Chen YQ, Ku YH. Properties of favored patterns in spontaneous spike trains and responses of favored patterns to electroacupuncture in evoked trains. Brain Res 1992;578(1-2):297-304.

Chen Z, Chen P. [Effects of morphine and electro-acupuncture on the time lock and not-time lock responses of cortical unit discharges evoked by nociceptive stimulation in cats]. Chen Tzu Yen Chiu 1991;16(2):95-9. (Chi).

Chen ZQ, Xu W, Lin Y. Identification of cortico-thalamic neurons: involvement of cortical descending modulation in acupuncture analgesia. J Tradit Chin Med 1986 Sep;6(3):195-200.

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