Skip Navigation Links
 



                     


 



   
    Learn More     Subscribe    
Join Now!      Login
 
 
 
FREE HEALTH
NEWSLETTER
 
 
Medicial Mistakes Quiz
How many people each year suffer some type of preventable harm that contributes to their death after a hospital visit?
 
 
 
 
W
hat Doctors Don't Tell You
 
ARTHRITIS
SECOND-LINE TERRORS

© What Doctors Don't Tell You (Volume 5, Issue 5)

Lack of research into long-term effects means the patient has to play a game of Russian roulette to discover whether he will develop symptoms worse than his condition. Fortunately, with gold treatment at least, an intolerance can usually be quickly spotted when the patient develops mouth sores or rashes.

Specialists do not understand how SAARDs work if and when they do but accept they can be highly toxic and even life-threatening (Drug and Therapeutics Bulletin, 1993; 31:18).

The overall impression is a stumble in the dark. As two American rheumatologists Joseph Cash and John Klippel concluded in their recent paper: ". . . substantial advances in the drug treatment of rheumatoid arthritis will require a much better understanding of the processes that propagate the disease and, ultimately, the identification of the factors that cause it." (New Eng Jrnl of Med, 12 May 1994).

Besides NSAIDS, here are the main orthodox treatments:

Gold

The traditional, and favoured, SAARD, even described by some rheumatologists as "the gold standard". A surprising title for a highly toxic treatment that can lead to fatal bone-marrow suppression (Drugs and Therapeutics Bulletin, 1993; 31: 18).

As it has been administered since the 1920s, it is staggering that there has never been a long-term trial to test for reactions.

It became the treatment of choice only because researchers misunderstood the causes of arthritis. German bacteriologist Robert Koch had shown that gold and other heavy metals could fight tuberculosis and other infectious diseases. As it was believed arthritis was an infection, the theory was that gold could treat it as well.

It can be administered either as an injection, the most common course, or in tablet form, introduced about seven years ago. The usual dose by injection is 50mg a week for 18 months, although the doctor should be monitoring carefully for early side effects such as skin rashes and mouth sores. More serious side effects include kidney problems and bone marrow suppression. Because of these concerns, gold tablets were developed. Early studies show they cause fewer side effects than injections (Arthritis Rheum 1990; 33: 1449-61), but conversely are also less efficacious (Ann Rheum Dis 1986; 45: 705-11).

Methotrexate

Methotrexate is fast becoming the most popular second-line therapy in the US as it is supposedly less toxic than gold (J Cash and J Klippel, cited above). This is an astounding statement to make about a powerful drug developed to treat cancer and, if true, can apply only at very low dosages.

The usual dosage is between five and 15mg a week, and improvements have been noted in between 30 and 70 per cent of patients (Eur J Rheumatol Inflamm 1991; 11: 148-61).

However, the typical side effects of stomach complaints, nausea and anorexia can worsen dramatically if the dose is increased or the drug mixed with another. Damage to the liver and lungs has been reported (Ann Rheum Dis 1990; 49: 25-7). Death can occur with high doses, especially if the patient takes the dose daily instead of weekly (Drugs and Therapeutics Bulletin, 1993; 31: 18).

Penicillamine

As the name sugggests, penicillamine is a component of penicillin and was originally developed to treat Wilson's disease (copper accumulation in the liver). For arthritis the daily maintenance dose can be as high as 750mg, although the patient is usually started with between 125 and 250mg to test for adverse reactions.

Add your comment   CONTINUED      Previous   1  2  3  Next   
About The Author
What Doctors Don’t Tell You is one of the few publications in the world that can justifiably claim to solve people's health problems - and even save lives. Our monthly newsletter gives you the facts you won't read anywhere else about what works, what doesn't work and what may harm you in both orthodox and alternative medicine. We'll also tell you how you can prevent illness.......more
Related Articles
 
Share   Facebook   Buzz   Delicious   Digg   Twitter  
 
 
 
 
 
 
From Our Sponsor
 
 
 
 
 
 
Featured Events
Wellness Inventory Certification Training
     September 16-December 16, 2014
     Teleclass, CA USA
 
Additional Calendar Links
 
Wellness, Communicating, dimension!

Search   
Home       Wellness       Health A-Z       Alternative Therapies       Find a Practitioner       Healthy Products       Bookstore       Wellness Inventory
Healthy Kitchen       Healthy Woman       Healthy Man       Healthy Child       Healthy Aging       Wellness Center       Nutrition Center       Fitness Center
Free Newsletter      What Doctor's Don't Tell You      Stevia.com      Discount Lab Tests      First Aid      Global Health Calendar      Privacy Policy     Contact Us

Disclaimer: The information provided on HealthWorld Online is for educational purposes only and IS NOT intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek professional medical advice from your physician or other qualified healthcare provider with any questions you may have regarding a medical condition.